Gene name: AP1S3

Uniprot entry:

Q96PC3

Protein names:

AP-1 complex subunit sigma-3 (Adaptor protein complex AP-1 subunit sigma-1C) (Adaptor-related protein complex 1 subunit sigma-1C) (Clathrin assembly protein complex 1 sigma-1C small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1C subunit) (Sigma 1C subunit of AP-1 clathrin) (Sigma-adaptin 1C) (Sigma1C-adaptin)

Protein sequence:

1_MIHFI 6_ LLFSR 11_ QGKLR 16_ LQKWY 21_ ITLPD 26_ KERKK 31_ ITREI 36_ VQIIL 41_ SRGHR 46_ TSSFV 51_ DWKEL 56_ KLVYK 61_ RYASL 66_ YFCCA 71_ IENQD 76_ NELLT 81_ LEIVH 86_ RYVEL 91_ LDKYF 96_ GNVCE 101_ LDIIF 106_ NFEKA 111_ YFILD 116_ EFIIG 121_ GEIQE 126_ TSKKI 131_ AVKAI 136_ EDSDM 141_ LQEVS 146_TVSQT

Protein annotations

Protein functions:

1: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Involved in TLR3 trafficking (PubMed:24791904)