Serine/threonine-protein kinase LMTK3 (EC 2.7.11.1) (Lemur tyrosine kinase 3)
1_MPAPG 6_ ALILL 11_ AAVSA 16_ SGCLA 21_ SPAHP 26_ DGFAL 31_ GRAPL 36_ APPYA 41_ VVLIS 46_ CSGLL 51_ AFIFL 56_ LLTCL 61_ CCKRG 66_ DVGFK 71_ EFENP 76_ EGEDC 81_ SGEYT 86_ PPAEE 91_ TSSSQ 96_ SLPDV 101_ YILPL 106_ AEVSL 111_ PMPAP 116_ QPSHS 121_ DMTTP 126_ LGLSR 131_ QHLSY 136_ LQEIG 141_ SGWFG 146_ KVILG 151_ EIFSD 156_ YTPAQ 161_ VVVKE 166_ LRASA 171_ GPLEQ 176_ RKFIS 181_ EAQPY 186_ RSLQH 191_ PNVLQ 196_ CLGLC 201_ VETLP 206_ FLLIM 211_ EFCQL 216_ GDLKR 221_ YLRAQ 226_ RPPEG 231_ LSPEL 236_ PPRDL 241_ RTLQR 246_ MGLEI 251_ ARGLA 256_ HLHSH 261_ NYVHS 266_ DLALR 271_ NCLLT 276_ SDLTV 281_ RIGDY 286_ GLAHS 291_ NYKED 296_ YYLTP 301_ ERLWI 306_ PLRWA 311_ APELL 316_ GELHG 321_ TFMVV 326_ DQSRE 331_ SNIWS 336_ LGVTL 341_ WELFE 346_ FGAQP 351_ YRHLS 356_ DEEVL 361_ AFVVR 366_ QQHVK 371_ LARPR 376_ LKLPY 381_ ADYWY 386_ DILQS 391_ CWRPP 396_ AQRPS 401_ ASDLQ 406_ LQLTY 411_ LLSER 416_ PPRPP 421_ PPPPP 426_ PRDGP 431_ FPWPW 436_ PPAHS 441_ APRPG 446_ TLSSP 451_ FPLLD 456_ GFPGA 461_ DPDDV 466_ LTVTE 471_ SSRGL 476_ NLECL 481_ WEKAR 486_ RGAGR 491_ GGGAP 496_ AWQPA 501_ SAPPA 506_ PHANP 511_ SNPFY 516_ EALST 521_ PSVLP 526_ VISAR 531_ SPSVS 536_ SEYYI 541_ RLEEH 546_ GSPPE 551_ PLFPN 556_ DWDPL 561_ DPGVP 566_ APQAP 571_ QAPSE 576_ VPQLV 581_ SETWA 586_ SPLFP 591_ APRPF 596_ PAQSS 601_ ASGSF 606_ LLSGW 611_ DPEGR 616_ GAGET 621_ LAGDP 626_ AEVLG 631_ ERGTA 636_ PWVEE 641_ EEEEE 646_ EGSSP 651_ GEDSS 656_ SLGGG 661_ PSRRG 666_ PLPCP 671_ LCSRE 676_ GACSC 681_ LPLER 686_ GDAVA 691_ GWGGH 696_ PALGC 701_ PHPPE 706_ DDSSL 711_ RAERG 716_ SLADL 721_ PMAPP 726_ ASAPP 731_ EFLDP 736_ LMGAA 741_ APQYP 746_ GRGPP 751_ PAPPP 756_ PPPPP 761_ RAPAD 766_ PAASP 771_ DPPSA 776_ VASPG 781_ SGLSS 786_ PGPKP 791_ GDSGY 796_ ETETP 801_ FSPEG 806_ AFPGG 811_ GAAEE 816_ EGVPR 821_ PRAPP 826_ EPPDP 831_ GAPRP 836_ PPDPG 841_ PLPLP 846_ GPREK 851_ PTFVV 856_ QVSTE 861_ QLLMS 866_ LREDV 871_ TRNLL 876_ GEKGA 881_ TARET 886_ GPRKA 891_ GRGPG 896_ NREKV 901_ PGLNR 906_ DPTVL 911_ GNGKQ 916_ APSLS 921_ LPVNG 926_ VTVLE 931_ NGDQR 936_ APGIE 941_ EKAAE 946_ NGALG 951_ SPERE 956_ EKVLE 961_ NGELT 966_ PPRRE 971_ EKALE 976_ NGELR 981_ SPEAG 986_ EKVLV 991_ NGGLT 996_ PPKSE 1001_ DKVSE 1006_ NGGLR 1011_ FPRNT 1016_ ERPPE 1021_ TGPWR 1026_ APGPW 1031_ EKTPE 1036_ SWGPA 1041_ PTIGE 1046_ PAPET 1051_ SLERA 1056_ PAPSA 1061_ VVSSR 1066_ NGGET 1071_ APGPL 1076_ GPAPK 1081_ NGTLE 1086_ PGTER 1091_ RAPET 1096_ GGAPR 1101_ APGAG 1106_ RLDLG 1111_ SGGRA 1116_ PVGTG 1121_ TAPGG 1126_ GPGSG 1131_ VDAKA 1136_ GWVDN 1141_ TRPQP 1146_ PPPPL 1151_ PPPPE 1156_ AQPRR 1161_ LEPAP 1166_ PRARP 1171_ EVAPE 1176_ GEPGA 1181_ PDSRA 1186_ GGDTA 1191_ LSGDG 1196_ DPPKP 1201_ ERKGP 1206_ EMPRL 1211_ FLDLG 1216_ PPQGN 1221_ SEQIK 1226_ ARLSR 1231_ LSLAL 1236_ PPLTL 1241_ TPFPG 1246_ PGPRR 1251_ PPWEG 1256_ ADAGA 1261_ AGGEA 1266_ GGAGA 1271_ PGPAE 1276_ EDGED 1281_ EDEDE 1286_ EEDEE 1291_ AAAPG 1296_ AAAGP 1301_ RGPGR 1306_ ARAAP 1311_ VPVVV 1316_ SSADA 1321_ DAARP 1326_ LRGLL 1331_ KSPRG 1336_ ADEPE 1341_ DSELE 1346_ RKRKM 1351_ VSFHG 1356_ DVTVY 1361_ LFDQE 1366_ TPTNE 1371_ LSVQA 1376_ PPEGD 1381_ TDPST 1386_ PPAPP 1391_ TPPHP 1396_ ATPGD 1401_ GFPSN 1406_ DSGFG 1411_ GSFEW 1416_ AEDFP 1421_ LLPPP 1426_ GPPLC 1431_ FSRFS 1436_ VSPAL 1441_ ETPGP 1446_ PARAP 1451_DARPA
1: Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed:21602804). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons (By similarity)