Heparan sulfate glucosamine 3-O-sulfotransferase 6 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6) (3-OST-6) (Heparan sulfate 3-O-sulfotransferase 6) (h3-OST-6)
1_MAGSG 6_ GLGGG 11_ AGGGQ 16_ GAGAG 21_ QGAAL 26_ RASRA 31_ PMLLV 36_ ALVLG 41_ AYCLC 46_ ALPGR 51_ CPPAA 56_ RAPAP 61_ APAPS 66_ EPSSS 71_ VHRPG 76_ APGLP 81_ LASGP 86_ GRRRF 91_ PQALI 96_ VGVKK 101_ GGTRA 106_ LLEFL 111_ RLHPD 116_ VRALG 121_ SEPHF 126_ FDRCY 131_ ERGLA 136_ WYRSL 141_ MPRTL 146_ DGQIT 151_ MEKTP 156_ SYFVT 161_ REAPR 166_ RIHAM 171_ SPDTK 176_ LIVVV 181_ RNPVT 186_ RAISD 191_ YAQTL 196_ SKTPG 201_ LPSFR 206_ ALAFR 211_ HGLGP 216_ VDTAW 221_ SAVRI 226_ GLYAQ 231_ HLDHW 236_ LRYFP 241_ LSHFL 246_ FVSGE 251_ RLVSD 256_ PAGEV 261_ GRVQD 266_ FLGLK 271_ RVVTD 276_ KHFYF 281_ NATKG 286_ FPCLK 291_ KAQGG 296_ SRPRC 301_ LGKSK 306_ GRPHP 311_ RVPQA 316_ LVRRL 321_ QEFYR 326_ PFNRR 331_ FYQMT 336_GQDFG
1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to heparan sulfate. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes Simplex Virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate