ATPase WRNIP1 (EC 3.6.1.-) (Werner helicase-interacting protein 1)
1_MEVSG 6_ PEDDP 11_ FLSQL 16_ HQVQC 21_ PVCQQ 26_ MMPAA 31_ HINSH 36_ LDRCL 41_ LLHPA 46_ GHAEP 51_ AAGSH 56_ RAGER 61_ AKGPS 66_ PPGAK 71_ RRRLS 76_ ESSAL 81_ KQPAT 86_ PTAAE 91_ SSEGE 96_ GEEGD 101_ DGGET 106_ ESRES 111_ YDAPP 116_ TPSGA 121_ RLIPD 126_ FPVAR 131_ SSSPG 136_ RKGSG 141_ KRPAA 146_ AAAAG 151_ SASPR 156_ SWDEA 161_ EAQEE 166_ EEAVG 171_ DGDGD 176_ GDADA 181_ DGEDD 186_ PGHWD 191_ ADAAE 196_ AATAF 201_ GASGG 206_ GRPHP 211_ RALAA 216_ EEIRQ 221_ MLQGK 226_ PLADT 231_ MRPDT 236_ LQDYF 241_ GQSKA 246_ VGQDT 251_ LLRSL 256_ LETNE 261_ IPSLI 266_ LWGPP 271_ GCGKT 276_ TLAHI 281_ IASNS 286_ KKHSI 291_ RFVTL 296_ SATNA 301_ KTNDV 306_ RDVIK 311_ QAQNE 316_ KSFFK 321_ RKTIL 326_ FIDEI 331_ HRFNK 336_ SQQDT 341_ FLPHV 346_ ECGTI 351_ TLIGA 356_ TTENP 361_ SFQVN 366_ AALLS 371_ RCRVI 376_ VLEKL 381_ PVEAM 386_ VTILM 391_ RAINS 396_ LGIHV 401_ LDSSR 406_ PTDPL 411_ SHSSN 416_ SSSEP 421_ AMFIE 426_ DKAVD 431_ TLAYL 436_ SDGDA 441_ RAGLN 446_ GLQLA 451_ VLARL 456_ SSRKM 461_ FCKKS 466_ GQSYS 471_ PSRVL 476_ ITEND 481_ VKEGL 486_ QRSHI 491_ LYDRA 496_ GEEHY 501_ NCISA 506_ LHKSM 511_ RGSDQ 516_ NASLY 521_ WLARM 526_ LEGGE 531_ DPLYV 536_ ARRLV 541_ RFASE 546_ DIGLA 551_ DPSAL 556_ TQAVA 561_ AYQGC 566_ HFIGM 571_ PECEV 576_ LLAQC 581_ VVYFA 586_ RAPKS 591_ IEVYS 596_ AYNNV 601_ KACLR 606_ NHQGP 611_ LPPVP 616_ LHLRN 621_ APTRL 626_ MKDLG 631_ YGKGY 636_ KYNPM 641_ YSEPV 646_ DQEYL 651_ PEELR 656_GVDFF
1: Functions as a modulator of initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. In the presence of ATP, stimulation of DNA polymerase delta-mediated DNA synthesis is decreased. Also plays a role in the innate immune defense against viruses. Stabilizes the RIGI dsRNA interaction and promotes RIGI 'Lys-63'-linked polyubiquitination. In turn, RIGI transmits the signal through mitochondrial MAVS