Ran-binding protein 9 (RanBP9) (BPM-L) (BPM90) (Ran-binding protein M) (RanBPM) (RanBP7)
1_MSGQP 6_ PPPPP 11_ QQQQQ 16_ QQQLS 21_ PPPPA 26_ ALAPV 31_ SGVVL 36_ PAPPA 41_ VSAGS 46_ SPAGS 51_ PGGGA 56_ GGEGL 61_ GAAAA 66_ ALLLH 71_ PPPPP 76_ PPATA 81_ APPPP 86_ PPPPP 91_ PPASA 96_ AAPAS 101_ GPPAP 106_ PGLAA 111_ GPGPA 116_ GGAPT 121_ PALVA 126_ GSSAA 131_ APFPH 136_ GDSAL 141_ NEQEK 146_ ELQRR 151_ LKRLY 156_ PAVDE 161_ QETPL 166_ PRSWS 171_ PKDKF 176_ SYIGL 181_ SQNNL 186_ RVHYK 191_ GHGKT 196_ PKDAA 201_ SVRAT 206_ HPIPA 211_ ACGIY 216_ YFEVK 221_ IVSKG 226_ RDGYM 231_ GIGLS 236_ AQGVN 241_ MNRLP 246_ GWDKH 251_ SYGYH 256_ GDDGH 261_ SFCSS 266_ GTGQP 271_ YGPTF 276_ TTGDV 281_ IGCCV 286_ NLINN 291_ TCFYT 296_ KNGHS 301_ LGIAF 306_ TDLPP 311_ NLYPT 316_ VGLQT 321_ PGEVV 326_ DANFG 331_ QHPFV 336_ FDIED 341_ YMREW 346_ RTKIQ 351_ AQIDR 356_ FPIGD 361_ REGEW 366_ QTMIQ 371_ KMVSS 376_ YLVHH 381_ GYCAT 386_ AEAFA 391_ RSTDQ 396_ TVLEE 401_ LASIK 406_ NRQRI 411_ QKLVL 416_ AGRMG 421_ EAIET 426_ TQQLY 431_ PSLLE 436_ RNPNL 441_ LFTLK 446_ VRQFI 451_ EMVNG 456_ TDSEV 461_ RCLGG 466_ RSPKS 471_ QDSYP 476_ VSPRP 481_ FSSPS 486_ MSPSH 491_ GMNIH 496_ NLASG 501_ KGSTA 506_ HFSGF 511_ ESCSN 516_ GVISN 521_ KAHQS 526_ YCHSN 531_ KHQSS 536_ NLNVP 541_ ELNSI 546_ NMSRS 551_ QQVNN 556_ FTSND 561_ VDMET 566_ DHYSN 571_ GVGET 576_ SSNGF 581_ LNGSS 586_ KHDHE 591_ MEDCD 596_ TEMEV 601_ DSSQL 606_ RRQLC 611_ GGSQA 616_ AIERM 621_ IHFGR 626_ ELQAM 631_ SEQLR 636_ RDCGK 641_ NTANK 646_ KMLKD 651_ AFSLL 656_ AYSDP 661_ WNSPV 666_ GNQLD 671_ PIQRE 676_ PVCSA 681_ LNSAI 686_ LETHN 691_ LPKQP 696_ PLALA 701_ MGQAT 706_ QCLGL 711_ MARSG 716_ IGSCA 721_FATVE
1: May act as scaffolding protein, and as adapter protein to couple membrane receptors to intracellular signaling pathways (Probable). Acts as a mediator of cell spreading and actin cytoskeleton rearrangement (PubMed:18710924). Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 (PubMed:29911972). May be involved in signaling of ITGB2/LFA-1 and other integrins (PubMed:14722085). Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway (PubMed:12147692). Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation (PubMed:12361945, PubMed:18222118). Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity (PubMed:15558019). Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA