CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215)
1_MMDLV 6_ LEEDV 11_ TVPGT 16_ LSGCS 21_ GLVPS 26_ VPDDL 31_ DGINP 36_ NAGLG 41_ NGLLP 46_ NVSEE 51_ TVSPT 56_ RARNM 61_ KDFEN 66_ QITEL 71_ KKENF 76_ NLKLR 81_ IYFLE 86_ ERMQQ 91_ EFHGP 96_ TEHIY 101_ KTNIE 106_ LKVEV 111_ ESLKR 116_ ELQER 121_ EQLLI 126_ KASKA 131_ VESLA 136_ EAGGS 141_ EIQRV 146_ KEDAR 151_ KKVQQ 156_ VEDLL 161_ TKRIL 166_ LLEKD 171_ VTAAQ 176_ AELEK 181_ AFAGT 186_ ETEKA 191_ LRLRL 196_ ESKLS 201_ EMKKM 206_ HEGDL 211_ AMALV 216_ LDEKD 221_ RLIEE 226_ LKLSL 231_ KSKEA 236_ LIQCL 241_ KEEKS 246_ QMACP 251_ DENVS 256_ SGELR 261_ GLCAA 266_ PREEK 271_ ERETE 276_ AAQME 281_ HQKER 286_ NSFEE 291_ RIQAL 296_ EEDLR 301_ EKERE 306_ IATEK 311_ KNSLK 316_ RDKAI 321_ QGLTM 326_ ALKSK 331_ EKKVE 336_ ELNSE 341_ IEKLS 346_ AAFAK 351_ AREAL 356_ QKAQT 361_ QEFQG 366_ SEDYE 371_ TALSG 376_ KEALS 381_ AALRS 386_ QNLTK 391_ STENH 396_ RLRRS 401_ IKKIT 406_ QELSD 411_ LQQER 416_ ERLEK 421_ DLEEA 426_ HREKS 431_ KGDCT 436_ IRDLR 441_ NEVEK 446_ LRNEV 451_ NEREK 456_ AMENR 461_ YKSLL 466_ SESNK 471_ KLHNQ 476_ EQVIK 481_ HLTES 486_ TNQKD 491_ VLLQK 496_ FNEKD 501_ LEVIQ 506_ QNCYL 511_ MAAED 516_ LELRS 521_ EGLIT 526_ EKCSS 531_ QQPPG 536_ SKTIF 541_ SKEKK 546_ QSSDY 551_ EELIQ 556_ VLKKE 561_ QDIYT 566_ HLVKS 571_ LQESD 576_ SINNL 581_ QAELN 586_ KIFAL 591_ RKQLE 596_ QDVLS 601_ YQNLR 606_ KTLEE 611_ QISEI 616_ RRREE 621_ ESFSL 626_ YSDQT 631_ SYLSI 636_ CLEEN 641_ NRFQV 646_ EHFSQ 651_ EELKK 656_ KVSDL 661_ IQLVK 666_ ELYTD 671_ NQHLK 676_ KTIFD 681_ LSCMG 686_ FQGNG 691_ FPDRL 696_ ASTEQ 701_ TELLA 706_ SKEDE 711_ DTIKI 716_ GEDDE 721_ INFLS 726_ DQHLQ 731_ QSNEI 736_ MKDLS 741_ KGGCK 746_ NGYLR 751_ HTESK 756_ ISDCD 761_ GAHAP 766_ GCLEE 771_ GAFIN 776_ LLAPL 781_ FNEKA 786_ TLLLE 791_ SRPDL 796_ LKVVR 801_ ELLLG 806_ QLFLT 811_ EQEVS 816_ GEHLD 821_ GKTEK 826_ TPKQK 831_ GELVH 836_ FVQTN 841_ SFSKP 846_ HDELK 851_ LSCEA 856_ QLVKA 861_ GEVPK 866_ VGLKD 871_ ASVQT 876_ VATEG 881_ DLLRF 886_ KHEAT 891_ REAWE 896_ EKPIN 901_ TALSA 906_ EHRPE 911_ NLHGV 916_ PGWQA 921_ ALLSL 926_ PGITN 931_ REAKK 936_ SRLPI 941_ LIKPS 946_ RSLGN 951_ MYRLP 956_ ATQEV 961_ VTQLQ 966_ SQILE 971_ LQGEL 976_ KEFKT 981_ CNKQL 986_ HQKLI 991_ LAEAV 996_ MEGRP 1001_ TPDKT 1006_ LLNAQ 1011_ PPVGA 1016_ AYQDS 1021_ PGEQK 1026_ GIKTT 1031_ SSVWR 1036_ DKEMD 1041_ SDQQR 1046_ SYEID 1051_ SEICP 1056_ PDDLA 1061_ SLPSC 1066_ KENPE 1071_ DVLSP 1076_ TSVAT 1081_ YLSSK 1086_ SQPSA 1091_ KVSVM 1096_ GTDQS 1101_ ESINT 1106_ SNETE 1111_ YLKQK 1116_ IHDLE 1121_ TELEG 1126_ YQNFI 1131_ FQLQK 1136_ HSQCS 1141_ EAIIT 1146_ VLCGT 1151_ EGAQD 1156_ GLSKP 1161_ KNGSD 1166_ GEEMT 1171_ FSSLH 1176_ QVRYV 1181_ KHVKI 1186_ LGPLA 1191_ PEMID 1196_ SRVLE 1201_ NLKQQ 1206_ LEEQE 1211_ YKLQK 1216_ EQNLN 1221_ MQLFS 1226_ EIHNL 1231_ QNKFR 1236_ DLSPP 1241_ RYDSL 1246_ VQSQA 1251_ RELSL 1256_ QRQQI 1261_ KDGHG 1266_ ICVIS 1271_ RQHMN 1276_ TMIKA 1281_ FEELL 1286_ QASDV 1291_ DYCVA 1296_ EGFQE 1301_ QLNQC 1306_ AELLE 1311_ KLEKL 1316_ FLNGK 1321_ SVGVE 1326_ MNTQN 1331_ ELMER 1336_ IEEDN 1341_ LTYQH 1346_ LLPES 1351_ PEPSA 1356_ SHALS 1361_ DYETS 1366_ EKSFF 1371_ SRDQK 1376_ QDNET 1381_ EKTSV 1386_ MVNSF 1391_ SQDLL 1396_ MEHIQ 1401_ EIRTL 1406_ RKRLE 1411_ ESIKT 1416_ NEKLR 1421_ KQLER 1426_ QGSEF 1431_ VQGST 1436_ SIFAS 1441_ GSELH 1446_ SSLTS 1451_ EIHFL 1456_ RKQNQ 1461_ ALNAM 1466_ LIKGS 1471_ RDKQK 1476_ ENDKL 1481_ RESLS 1486_ RKTVS 1491_ LEHLQ 1496_ REYAS 1501_ VKEEN 1506_ ERLQK 1511_ EGSEK 1516_ ERHNQ 1521_ QLIQE 1526_ VRCSG 1531_ QELSR 1536_ VQEEV 1541_ KLRQQ 1546_ LLSQN 1551_ DKLLQ 1556_ SLRVE 1561_ LKAYE 1566_ KLDEE 1571_ HRRLR 1576_ EASGE 1581_ GWKGQ 1586_ DPFRD 1591_ LHSLL 1596_ MEIQA 1601_ LRLQL 1606_ ERSIE 1611_ TSSTL 1616_ QSRLK 1621_ EQLAR 1626_ GAEKA 1631_ QEGAL 1636_ TLAVQ 1641_ AVSIP 1646_ EVPLQ 1651_ PDKHD 1656_ GDKYP 1661_ MESDN 1666_ SFDLF 1671_ DSSQA 1676_ VTPKS 1681_ VSETP 1686_ PLSGN 1691_ DTDSL 1696_ SCDSG 1701_ SSATS 1706_ TPCVS 1711_ RLVTG 1716_ HHLWA 1721_ SKNGR 1726_ HVLGL 1731_ IEDYE 1736_ ALLKQ 1741_ ISQGQ 1746_ RLLAE 1751_ MDIQT 1756_ QEAPS 1761_ STSQE 1766_ LGTKG 1771_ PHPAP 1776_ LSKFV 1781_ SSVST 1786_ AKLTL 1791_ EEAYR 1796_ RLKLL 1801_ WRVSL 1806_ PEDGQ 1811_ CPLHC 1816_ EQIGE 1821_ MKAEV 1826_ TKLHK 1831_ KLFEQ 1836_ EKKLQ 1841_ NTMKL 1846_ LQLSK 1851_ RQEKV 1856_ IFDQL 1861_ VVTHK 1866_ ILRKA 1871_ RGNLE 1876_ LRPGG 1881_ AHPGT 1886_CSPSR
1: Potential regulator of CDK5 activity via its interaction with CDK5R1 (PubMed:15164053). Negative regulator of centriole disengagement (licensing) which maintains centriole engagement and cohesion. Involved in regulation of mitotic spindle orientation (By similarity). Plays a role in the spindle checkpoint activation by acting as a transcriptional regulator of both BUBR1 and MAD2 promoter (PubMed:19282672). Together with EB1/MAPRE1, may promote microtubule polymerization, bundle formation, growth and dynamics at the plus ends (PubMed:18042621, PubMed:17959831, PubMed:19553473). Regulates centrosomal maturation by recruitment of the gamma-tubulin ring complex (gTuRC) onto centrosomes (PubMed:18042621, PubMed:17959831, PubMed:26485573, PubMed:39321809). In complex with PDE4DIP isoform 13/MMG8/SMYLE, MAPRE1 and AKAP9, contributes to microtubules nucleation and extension from the centrosome to the cell periphery (PubMed:29162697). Required for the recruitment of AKAP9 to centrosomes (PubMed:29162697). Plays a role in neurogenesis (By similarity)