Sodium channel protein type 2 subunit alpha (HBSC II) (Sodium channel protein brain II subunit alpha) (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2)
1_MAQSV 6_ LVPPG 11_ PDSFR 16_ FFTRE 21_ SLAAI 26_ EQRIA 31_ EEKAK 36_ RPKQE 41_ RKDED 46_ DENGP 51_ KPNSD 56_ LEAGK 61_ SLPFI 66_ YGDIP 71_ PEMVS 76_ VPLED 81_ LDPYY 86_ INKKT 91_ FIVLN 96_ KGKAI 101_ SRFSA 106_ TPALY 111_ ILTPF 116_ NPIRK 121_ LAIKI 126_ LVHSL 131_ FNMLI 136_ MCTIL 141_ TNCVF 146_ MTMSN 151_ PPDWT 156_ KNVEY 161_ TFTGI 166_ YTFES 171_ LIKIL 176_ ARGFC 181_ LEDFT 186_ FLRDP 191_ WNWLD 196_ FTVIT 201_ FAYVT 206_ EFVDL 211_ GNVSA 216_ LRTFR 221_ VLRAL 226_ KTISV 231_ IPGLK 236_ TIVGA 241_ LIQSV 246_ KKLSD 251_ VMILT 256_ VFCLS 261_ VFALI 266_ GLQLF 271_ MGNLR 276_ NKCLQ 281_ WPPDN 286_ SSFEI 291_ NITSF 296_ FNNSL 301_ DGNGT 306_ TFNRT 311_ VSIFN 316_ WDEYI 321_ EDKSH 326_ FYFLE 331_ GQNDA 336_ LLCGN 341_ SSDAG 346_ QCPEG 351_ YICVK 356_ AGRNP 361_ NYGYT 366_ SFDTF 371_ SWAFL 376_ SLFRL 381_ MTQDF 386_ WENLY 391_ QLTLR 396_ AAGKT 401_ YMIFF 406_ VLVIF 411_ LGSFY 416_ LINLI 421_ LAVVA 426_ MAYEE 431_ QNQAT 436_ LEEAE 441_ QKEAE 446_ FQQML 451_ EQLKK 456_ QQEEA 461_ QAAAA 466_ AASAE 471_ SRDFS 476_ GAGGI 481_ GVFSE 486_ SSSVA 491_ SKLSS 496_ KSEKE 501_ LKNRR 506_ KKKKQ 511_ KEQSG 516_ EEEKN 521_ DRVRK 526_ SESED 531_ SIRRK 536_ GFRFS 541_ LEGSR 546_ LTYEK 551_ RFSSP 556_ HQSLL 561_ SIRGS 566_ LFSPR 571_ RNSRA 576_ SLFSF 581_ RGRAK 586_ DIGSE 591_ NDFAD 596_ DEHST 601_ FEDND 606_ SRRDS 611_ LFVPH 616_ RHGER 621_ RHSNV 626_ SQASR 631_ ASRVL 636_ PILPM 641_ NGKMH 646_ SAVDC 651_ NGVVS 656_ LVGGP 661_ STLTS 666_ AGQLL 671_ PEGTT 676_ TETEI 681_ RKRRS 686_ SSYHV 691_ SMDLL 696_ EDPTS 701_ RQRAM 706_ SIASI 711_ LTNTM 716_ EELEE 721_ SRQKC 726_ PPCWY 731_ KFANM 736_ CLIWD 741_ CCKPW 746_ LKVKH 751_ LVNLV 756_ VMDPF 761_ VDLAI 766_ TICIV 771_ LNTLF 776_ MAMEH 781_ YPMTE 786_ QFSSV 791_ LSVGN 796_ LVFTG 801_ IFTAE 806_ MFLKI 811_ IAMDP 816_ YYYFQ 821_ EGWNI 826_ FDGFI 831_ VSLSL 836_ MELGL 841_ ANVEG 846_ LSVLR 851_ SFRLL 856_ RVFKL 861_ AKSWP 866_ TLNML 871_ IKIIG 876_ NSVGA 881_ LGNLT 886_ LVLAI 891_ IVFIF 896_ AVVGM 901_ QLFGK 906_ SYKEC 911_ VCKIS 916_ NDCEL 921_ PRWHM 926_ HDFFH 931_ SFLIV 936_ FRVLC 941_ GEWIE 946_ TMWDC 951_ MEVAG 956_ QTMCL 961_ TVFMM 966_ VMVIG 971_ NLVVL 976_ NLFLA 981_ LLLSS 986_ FSSDN 991_ LAATD 996_ DDNEM 1001_ NNLQI 1006_ AVGRM 1011_ QKGID 1016_ FVKRK 1021_ IREFI 1026_ QKAFV 1031_ RKQKA 1036_ LDEIK 1041_ PLEDL 1046_ NNKKD 1051_ SCISN 1056_ HTTIE 1061_ IGKDL 1066_ NYLKD 1071_ GNGTT 1076_ SGIGS 1081_ SVEKY 1086_ VVDES 1091_ DYMSF 1096_ INNPS 1101_ LTVTV 1106_ PIAVG 1111_ ESDFE 1116_ NLNTE 1121_ EFSSE 1126_ SDMEE 1131_ SKEKL 1136_ NATSS 1141_ SEGST 1146_ VDIGA 1151_ PAEGE 1156_ QPEVE 1161_ PEESL 1166_ EPEAC 1171_ FTEDC 1176_ VRKFK 1181_ CCQIS 1186_ IEEGK 1191_ GKLWW 1196_ NLRKT 1201_ CYKIV 1206_ EHNWF 1211_ ETFIV 1216_ FMILL 1221_ SSGAL 1226_ AFEDI 1231_ YIEQR 1236_ KTIKT 1241_ MLEYA 1246_ DKVFT 1251_ YIFIL 1256_ EMLLK 1261_ WVAYG 1266_ FQVYF 1271_ TNAWC 1276_ WLDFL 1281_ IVDVS 1286_ LVSLT 1291_ ANALG 1296_ YSELG 1301_ AIKSL 1306_ RTLRA 1311_ LRPLR 1316_ ALSRF 1321_ EGMRV 1326_ VVNAL 1331_ LGAIP 1336_ SIMNV 1341_ LLVCL 1346_ IFWLI 1351_ FSIMG 1356_ VNLFA 1361_ GKFYH 1366_ CINYT 1371_ TGEMF 1376_ DVSVV 1381_ NNYSE 1386_ CKALI 1391_ ESNQT 1396_ ARWKN 1401_ VKVNF 1406_ DNVGL 1411_ GYLSL 1416_ LQVAT 1421_ FKGWM 1426_ DIMYA 1431_ AVDSR 1436_ NVELQ 1441_ PKYED 1446_ NLYMY 1451_ LYFVI 1456_ FIIFG 1461_ SFFTL 1466_ NLFIG 1471_ VIIDN 1476_ FNQQK 1481_ KKFGG 1486_ QDIFM 1491_ TEEQK 1496_ KYYNA 1501_ MKKLG 1506_ SKKPQ 1511_ KPIPR 1516_ PANKF 1521_ QGMVF 1526_ DFVTK 1531_ QVFDI 1536_ SIMIL 1541_ ICLNM 1546_ VTMMV 1551_ ETDDQ 1556_ SQEMT 1561_ NILYW 1566_ INLVF 1571_ IVLFT 1576_ GECVL 1581_ KLISL 1586_ RYYYF 1591_ TIGWN 1596_ IFDFV 1601_ VVILS 1606_ IVGMF 1611_ LAELI 1616_ EKYFV 1621_ SPTLF 1626_ RVIRL 1631_ ARIGR 1636_ ILRLI 1641_ KGAKG 1646_ IRTLL 1651_ FALMM 1656_ SLPAL 1661_ FNIGL 1666_ LLFLV 1671_ MFIYA 1676_ IFGMS 1681_ NFAYV 1686_ KREVG 1691_ IDDMF 1696_ NFETF 1701_ GNSMI 1706_ CLFQI 1711_ TTSAG 1716_ WDGLL 1721_ APILN 1726_ SGPPD 1731_ CDPDK 1736_ DHPGS 1741_ SVKGD 1746_ CGNPS 1751_ VGIFF 1756_ FVSYI 1761_ IISFL 1766_ VVVNM 1771_ YIAVI 1776_ LENFS 1781_ VATEE 1786_ SAEPL 1791_ SEDDF 1796_ EMFYE 1801_ VWEKF 1806_ DPDAT 1811_ QFIEF 1816_ AKLSD 1821_ FADAL 1826_ DPPLL 1831_ IAKPN 1836_ KVQLI 1841_ AMDLP 1846_ MVSGD 1851_ RIHCL 1856_ DILFA 1861_ FTKRV 1866_ LGESG 1871_ EMDAL 1876_ RIQME 1881_ ERFMA 1886_ SNPSK 1891_ VSYEP 1896_ ITTTL 1901_ KRKQE 1906_ EVSAI 1911_ IIQRA 1916_ YRRYL 1921_ LKQKV 1926_ KKVSS 1931_ IYKKD 1936_ KGKEC 1941_ DGTPI 1946_ KEDTL 1951_ IDKLN 1956_ ENSTP 1961_ EKTDM 1966_ TPSTT 1971_ SPPSY 1976_ DSVTK 1981_ PEKEK 1986_ FEKDK 1991_ SEKED 1996_KGKDI
1: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient (PubMed:1325650, PubMed:17021166, PubMed:28256214, PubMed:29844171). Implicated in the regulation of hippocampal replay occurring within sharp wave ripples (SPW-R) important for memory (By similarity)