Tubulin-folding cofactor B (Cytoskeleton-associated protein 1) (Cytoskeleton-associated protein CKAPI) (Tubulin-specific chaperone B)
1_MEVTG 6_ VSAPT 11_ VTVFI 16_ SSSLN 21_ TFRSE 26_ KRYSR 31_ SLTIA 36_ EFKCK 41_ LELLV 46_ GSPAS 51_ CMELE 56_ LYGVD 61_ DKFYS 66_ KLDQE 71_ DALLG 76_ SYPVD 81_ DGCRI 86_ HVIDH 91_ SGARL 96_ GEYED 101_ VSRVE 106_ KYTIS 111_ QEAYD 116_ QRQDT 121_ VRSFL 126_ KRSKL 131_ GRYNE 136_ EERAQ 141_ QEAEA 146_ AQRLA 151_ EEKAQ 156_ ASSIP 161_ VGSRC 166_ EVRAA 171_ GQSPR 176_ RGTVM 181_ YVGLT 186_ DFKPG 191_ YWIGV 196_ RYDEP 201_ LGKND 206_ GSVNG 211_ KRYFE 216_ CQAKY 221_ GAFVK 226_ PAVVT 231_ VGDFP 236_EEDYG
1: Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer (PubMed:9265649). Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth (By similarity)