Gene name: ATP6V0B

Uniprot entry:

Q99437

Protein names:

V-type proton ATPase 21 kDa proteolipid subunit c'' (V-ATPase 21 kDa proteolipid subunit c'') (Vacuolar proton pump 21 kDa proteolipid subunit c'') (hATPL)

Protein sequence:

1_MTGLA 6_ LLYSG 11_ VFVAF 16_ WACAL 21_ AVGVC 26_ YTIFD 31_ LGFRF 36_ DVAWF 41_ LTETS 46_ PFMWS 51_ NLGIG 56_ LAISL 61_ SVVGA 66_ AWGIY 71_ ITGSS 76_ IIGGG 81_ VKAPR 86_ IKTKN 91_ LVSII 96_ FCEAV 101_ AIYGI 106_ IMAIV 111_ ISNMA 116_ EPFSA 121_ TDPKA 126_ IGHRN 131_ YHAGY 136_ SMFGA 141_ GLTVG 146_ LSNLF 151_ CGVCV 156_ GIVGS 161_ GAALA 166_ DAQNP 171_ SLFVK 176_ ILIVE 181_ IFGSA 186_ IGLFG 191_ VIVAI 196_LQTSR

Protein annotations

Protein functions:

1: Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:33065002). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity)