Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) (CTP:phosphoethanolamine cytidylyltransferase) (Phosphorylethanolamine transferase)
1_MIRNG 6_ RGAAG 11_ GAEQP 16_ GPGGR 21_ RAVRV 26_ WCDGC 31_ YDMVH 36_ YGHSN 41_ QLRQA 46_ RAMGD 51_ YLIVG 56_ VHTDE 61_ EIAKH 66_ KGPPV 71_ FTQEE 76_ RYKMV 81_ QAIKW 86_ VDEVV 91_ PAAPY 96_ VTTLE 101_ TLDKY 106_ NCDFC 111_ VHGND 116_ ITLTV 121_ DGRDT 126_ YEEVK 131_ QAGRY 136_ RECKR 141_ TQGVS 146_ TTDLV 151_ GRMLL 156_ VTKAH 161_ HSSQE 166_ MSSEY 171_ REYAD 176_ SFGKC 181_ PGGRN 186_ PWTGV 191_ SQFLQ 196_ TSQKI 201_ IQFAS 206_ GKEPQ 211_ PGETV 216_ IYVAG 221_ AFDLF 226_ HIGHV 231_ DFLEK 236_ VHRLA 241_ ERPYI 246_ IAGLH 251_ FDQEV 256_ NHYKG 261_ KNYPI 266_ MNLHE 271_ RTLSV 276_ LACRY 281_ VSEVV 286_ IGAPY 291_ AVTAE 296_ LLSHF 301_ KVDLV 306_ CHGKT 311_ EIIPD 316_ RDGSD 321_ PYQEP 326_ KRRGI 331_ FRQID 336_ SGSNL 341_ TTDLI 346_ VQRII 351_ TNRLE 356_ YEARN 361_ QKKEA 366_ KELAF 371_ LEAAR 376_ QQAAQ 381_PLGER
1: Ethanolamine-phosphate cytidylyltransferase that catalyzes the second step in the synthesis of phosphatidylethanolamine (PE) from ethanolamine via the CDP-ethanolamine pathway (PubMed:31637422, PubMed:9083101). Phosphatidylethanolamine is a dominant inner-leaflet phospholipid in cell membranes, where it plays a role in membrane function by structurally stabilizing membrane-anchored proteins, and participates in important cellular processes such as cell division, cell fusion, blood coagulation, and apoptosis (PubMed:9083101)