Histone H4-like protein type G (H4-clustered histone 7)
1_MSVRG 6_ KAGKG 11_ LGKGG 16_ AKCHR 21_ KVLSD 26_ NIQGI 31_ TKCTI 36_ RRLAR 41_ HGGVK 46_ RILGL 51_ IYEET 56_ RRVFK 61_ VFLEN 66_ VIWYA 71_ VTNTE 76_ HAKRK 81_ TVTAM 86_ AVVYV 91_LKRQG
1: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity)