Gene name: MTERF1

Uniprot entry:

Q99551

Protein names:

Transcription termination factor 1, mitochondrial (Mitochondrial transcription termination factor 1) (mTERF) (mTERF1)

Protein sequence:

1_MQSLS 6_ LGQTS 11_ ISKGL 16_ NYLTI 21_ MAPGN 26_ LWHMR 31_ NNFLF 36_ GSRCW 41_ MTRFS 46_ AENIF 51_ KSVSF 56_ RLFGV 61_ KCHNT 66_ DSEPL 71_ KNEDL 76_ LKNLL 81_ TMGVD 86_ IDMAR 91_ KRQPG 96_ VFHRM 101_ ITNEQ 106_ DLKMF 111_ LLSKG 116_ ASKEV 121_ IASII 126_ SRYPR 131_ AITRT 136_ PENLS 141_ KRWDL 146_ WRKIV 151_ TSDLE 156_ IVNIL 161_ ERSPE 166_ SFFRS 171_ NNNLN 176_ LENNI 181_ KFLYS 186_ VGLTR 191_ KCLCR 196_ LLTNA 201_ PRTFS 206_ NSLDL 211_ NKQMV 216_ EFLQA 221_ AGLSL 226_ GHNDP 231_ ADFVR 236_ KIIFK 241_ NPFIL 246_ IQSTK 251_ RVKAN 256_ IEFLR 261_ STFNL 266_ NSEEL 271_ LVLIC 276_ GPGAE 281_ ILDLS 286_ NDYAR 291_ RSYAN 296_ IKEKL 301_ FSLGC 306_ TEEEV 311_ QKFVL 316_ SYPDV 321_ IFLAE 326_ KKFND 331_ KIDCL 336_ MEENI 341_ SISQI 346_ IENPR 351_ VLDSS 356_ ISTLK 361_ SRIKE 366_ LVNAG 371_ CNLST 376_ LNITL 381_ LSWSK 386_ KRYEA 391_KLKKL

Protein annotations

Protein functions:

1: Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Transcription termination activity appears to be polarized with highest specificity for transcripts initiated on the light strand