Neuroserpin (Peptidase inhibitor 12) (PI-12) (Serpin I1)
1_MAFLG 6_ LFSLL 11_ VLQSM 16_ ATGAT 21_ FPEEA 26_ IADLS 31_ VNMYN 36_ RLRAT 41_ GEDEN 46_ ILFSP 51_ LSIAL 56_ AMGMM 61_ ELGAQ 66_ GSTQK 71_ EIRHS 76_ MGYDS 81_ LKNGE 86_ EFSFL 91_ KEFSN 96_ MVTAK 101_ ESQYV 106_ MKIAN 111_ SLFVQ 116_ NGFHV 121_ NEEFL 126_ QMMKK 131_ YFNAA 136_ VNHVD 141_ FSQNV 146_ AVANY 151_ INKWV 156_ ENNTN 161_ NLVKD 166_ LVSPR 171_ DFDAA 176_ TYLAL 181_ INAVY 186_ FKGNW 191_ KSQFR 196_ PENTR 201_ TFSFT 206_ KDDES 211_ EVQIP 216_ MMYQQ 221_ GEFYY 226_ GEFSD 231_ GSNEA 236_ GGIYQ 241_ VLEIP 246_ YEGDE 251_ ISMML 256_ VLSRQ 261_ EVPLA 266_ TLEPL 271_ VKAQL 276_ VEEWA 281_ NSVKK 286_ QKVEV 291_ YLPRF 296_ TVEQE 301_ IDLKD 306_ VLKAL 311_ GITEI 316_ FIKDA 321_ NLTGL 326_ SDNKE 331_ IFLSK 336_ AIHKS 341_ FLEVN 346_ EEGSE 351_ AAAVS 356_ GMIAI 361_ SRMAV 366_ LYPQV 371_ IVDHP 376_ FFFLI 381_ RNRRT 386_ GTILF 391_ MGRVM 396_ HPETM 401_NTSGH
1: Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin (PubMed:11880376, PubMed:19265707, PubMed:19285087, PubMed:26329378, PubMed:9442076). May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator (Probable)