Gene name: SDHC

Uniprot entry:

Q99643

Protein names:

Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (Integral membrane protein CII-3) (QPs-1) (QPs1) (Succinate dehydrogenase complex subunit C) (Succinate-ubiquinone oxidoreductase cytochrome B large subunit) (CYBL)

Protein sequence:

1_MAALL 6_ LRHVG 11_ RHCLR 16_ AHFSP 21_ QLCIR 26_ NAVPL 31_ GTTAK 36_ EEMER 41_ FWNKN 46_ IGSNR 51_ PLSPH 56_ ITIYS 61_ WSLPM 66_ AMSIC 71_ HRGTG 76_ IALSA 81_ GVSLF 86_ GMSAL 91_ LLPGN 96_ FESYL 101_ ELVKS 106_ LCLGP 111_ ALIHT 116_ AKFAL 121_ VFPLM 126_ YHTWN 131_ GIRHL 136_ MWDLG 141_ KGLKI 146_ PQLYQ 151_ SGVVV 156_ LVLTV 161_LSSMG

Protein annotations

Protein functions:

1: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (PubMed:9533030). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate (By similarity). Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate (By similarity)