ATP-sensitive inward rectifier potassium channel 15 (Inward rectifier K(+) channel Kir1.3) (Inward rectifier K(+) channel Kir4.2) (Potassium channel, inwardly rectifying subfamily J member 15)
1_MDAIH 6_ IGMSS 11_ TPLVK 16_ HTAGA 21_ GLKAN 26_ RPRVM 31_ SKSGH 36_ SNVRI 41_ DKVDG 46_ IYLLY 51_ LQDLW 56_ TTVID 61_ MKWRY 66_ KLTLF 71_ AATFV 76_ MTWFL 81_ FGVIY 86_ YAIAF 91_ IHGDL 96_ EPGEP 101_ ISNHT 106_ PCIMK 111_ VDSLT 116_ GAFLF 121_ SLESQ 126_ TTIGY 131_ GVRSI 136_ TEECP 141_ HAIFL 146_ LVAQL 151_ VITTL 156_ IEIFI 161_ TGTFL 166_ AKIAR 171_ PKKRA 176_ ETIKF 181_ SHCAV 186_ ITKQN 191_ GKLCL 196_ VIQVA 201_ NMRKS 206_ LLIQC 211_ QLSGK 216_ LLQTH 221_ VTKEG 226_ ERILL 231_ NQATV 236_ KFHVD 241_ SSSES 246_ PFLIL 251_ PMTFY 256_ HVLDE 261_ TSPLR 266_ DLTPQ 271_ NLKEK 276_ EFELV 281_ VLLNA 286_ TVEST 291_ SAVCQ 296_ SRTSY 301_ IPEEI 306_ YWGFE 311_ FVPVV 316_ SLSKN 321_ GKYVA 326_ DFSQF 331_ EQIRK 336_ SPDCT 341_ FYCAD 346_ SEKQQ 351_ LEEKY 356_ RQEDQ 361_ REREL 366_RTLLL
1: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium