C-C motif chemokine 19 (Beta-chemokine exodus-3) (CK beta-11) (Epstein-Barr virus-induced molecule 1 ligand chemokine) (EBI1 ligand chemokine) (ELC) (Macrophage inflammatory protein 3 beta) (MIP-3-beta) (Small-inducible cytokine A19)
1_MALLL 6_ ALSLL 11_ VLWTS 16_ PAPTL 21_ SGTND 26_ AEDCC 31_ LSVTQ 36_ KPIPG 41_ YIVRN 46_ FHYLL 51_ IKDGC 56_ RVPAV 61_ VFTTL 66_ RGRQL 71_ CAPPD 76_ QPWVE 81_ RIIQR 86_ LQRTS 91_AKMKR
1: May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4