Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2)
1_MAQRL 6_ LLRRF 11_ LASVI 16_ SRKPS 21_ QGQWP 26_ PLTSR 31_ ALQTP 36_ QCSPG 41_ GLTVT 46_ PNPAR 51_ TIYTT 56_ RISLT 61_ TFNIQ 66_ DGPDF 71_ QDRVV 76_ NSETP 81_ VVVDF 86_ HAQWC 91_ GPCKI 96_ LGPRL 101_ EKMVA 106_ KQHGK 111_ VVMAK 116_ VDIDD 121_ HTDLA 126_ IEYEV 131_ SAVPT 136_ VLAMK 141_ NGDVV 146_ DKFVG 151_ IKDED 156_ QLEAF 161_LKKLI
1: Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability (PubMed:12032145, PubMed:12080052, PubMed:26626369) Is involved in various redox reactions including the reduction of protein disulfide bonds, through the reversible oxidation of its active center dithiol to a disulfide (By similarity)