Rho GDP-dissociation inhibitor 3 (Rho GDI 3) (Rho-GDI gamma)
1_MLGLD 6_ ACELG 11_ AQLLE 16_ LLRLA 21_ LCARV 26_ LLADK 31_ EGGPP 36_ AVDEV 41_ LDEAV 46_ PEYRA 51_ PGRKS 56_ LLEIR 61_ QLDPD 66_ DRSLA 71_ KYKRV 76_ LLGPL 81_ PPAVD 86_ PSLPN 91_ VQVTR 96_ LTLLS 101_ EQAPG 106_ PVVMD 111_ LTGDL 116_ AVLKD 121_ QVFVL 126_ KEGVD 131_ YRVKI 136_ SFKVH 141_ REIVS 146_ GLKCL 151_ HHTYR 156_ RGLRV 161_ DKTVY 166_ MVGSY 171_ GPSAQ 176_ EYEFV 181_ TPVEE 186_ APRGA 191_ LVRGP 196_ YLVVS 201_ LFTDD 206_ DRTHH 211_ LSWEW 216_GLCIC
1: Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP