Protein NipSnap homolog 1 (NipSnap1)
1_MAPRL 6_ CSISV 11_ TARRL 16_ LGGPG 21_ PRAGD 26_ VASAA 31_ AARFY 36_ SKDNE 41_ GSWFR 46_ SLFVH 51_ KVDPR 56_ KDAHS 61_ TLLSK 66_ KETSN 71_ LYKIQ 76_ FHNVK 81_ PEYLD 86_ AYNSL 91_ TEAVL 96_ PKLHL 101_ DEDYP 106_ CSLVG 111_ NWNTW 116_ YGEQD 121_ QAVHL 126_ WRFSG 131_ GYPAL 136_ MDCMN 141_ KLKNN 146_ KEYLE 151_ FRRER 156_ SQMLL 161_ SRRNQ 166_ LLLEF 171_ SFWNE 176_ PQPRM 181_ GPNIY 186_ ELRTY 191_ KLKPG 196_ TMIEW 201_ GNNWA 206_ RAIKY 211_ RQENQ 216_ EAVGG 221_ FFSQI 226_ GELYV 231_ VHHLW 236_ AYKDL 241_ QSREE 246_ TRNAA 251_ WRKRG 256_ WDENV 261_ YYTVP 266_ LVRHM 271_ ESRIM 276_IPLKI
1: Protein involved in mitophagy by facilitating recruitment of the autophagy machinery required for clearance of damaged mitochondria (PubMed:30982665). Accumulates on the mitochondria surface in response to mitochondrial depolarization and acts as a 'eat me' signal by recruiting proteins involved in selective autophagy, such as autophagy receptors (CALCOCO2/NDP52, NBR1, SQSTM1/p62, TAX1BP1 and WDFY3/ALFY) and ATG8 family proteins (MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAP, GABARAPL1 and GABARAPL2) (PubMed:30982665)