Zinc finger FYVE domain-containing protein 21 (ZF21)
1_MSSEV 6_ SARRD 11_ AKKLV 16_ RSPSG 21_ LRMVP 26_ EHRAF 31_ GSPFG 36_ LEEPQ 41_ WVPDK 46_ ECRRC 51_ MQCDA 56_ KFDFL 61_ TRKHH 66_ CRRCG 71_ KCFCD 76_ RCCSQ 81_ KVPLR 86_ RMCFV 91_ DPVRQ 96_ CAECA 101_ LVSLK 106_ EAEFY 111_ DKQLK 116_ VLLSG 121_ ATFLV 126_ TFGNS 131_ EKPET 136_ MTCRL 141_ SNNQR 146_ YLFLD 151_ GDSHY 156_ EIEIV 161_ HISTV 166_ QILTE 171_ GFPPG 176_ GGNAR 181_ ATGMF 186_ LQYTV 191_ PGTEG 196_ VTQLK 201_ LTVVE 206_ DVTVG 211_ RRQAV 216_ AWLVA 221_ MHKAA 226_KLLYE
1: Plays a role in cell adhesion, and thereby in cell motility which requires repeated formation and disassembly of focal adhesions. Regulates microtubule-induced PTK2/FAK1 dephosphorylation, an event important for focal adhesion disassembly, as well as integrin beta-1/ITGB1 cell surface expression