Gene name: PDCD1LG2

Uniprot entry:

Q9BQ51

Protein names:

Programmed cell death 1 ligand 2 (PD-1 ligand 2) (PD-L2) (PDCD1 ligand 2) (Programmed death ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD antigen CD273)

Protein sequence:

1_MIFLL 6_ LMLSL 11_ ELQLH 16_ QIAAL 21_ FTVTV 26_ PKELY 31_ IIEHG 36_ SNVTL 41_ ECNFD 46_ TGSHV 51_ NLGAI 56_ TASLQ 61_ KVEND 66_ TSPHR 71_ ERATL 76_ LEEQL 81_ PLGKA 86_ SFHIP 91_ QVQVR 96_ DEGQY 101_ QCIII 106_ YGVAW 111_ DYKYL 116_ TLKVK 121_ ASYRK 126_ INTHI 131_ LKVPE 136_ TDEVE 141_ LTCQA 146_ TGYPL 151_ AEVSW 156_ PNVSV 161_ PANTS 166_ HSRTP 171_ EGLYQ 176_ VTSVL 181_ RLKPP 186_ PGRNF 191_ SCVFW 196_ NTHVR 201_ ELTLA 206_ SIDLQ 211_ SQMEP 216_ RTHPT 221_ WLLHI 226_ FIPFC 231_ IIAFI 236_ FIATV 241_ IALRK 246_ QLCQK 251_ LYSSK 256_ DTTKR 261_ PVTTT 266_KREVN

Protein annotations

Protein functions:

1: Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity)