Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12)
1_MVNSC 6_ CGSVC 11_ SDQGC 16_ GLENC 21_ CRPSC 26_ CQTTC 31_ CRTTC 36_ CRPSC 41_ CVSSC 46_ CRPQC 51_ CQSVC 56_ CQPTC 61_ CRPSC 66_ CQTTC 71_ CRTTC 76_ CRPSC 81_ CVSSC 86_ CRPQC 91_ CQSVC 96_ CQPTC 101_ CRPSC 106_ CQTTC 111_ CRTTC 116_ CRPSC 121_ CVSSC 126_ CRPQC 131_ CQSVC 136_ CQPTC 141_ CRPSC 146_ CISSS 151_ CCPSC 156_ CESSC 161_ CRPCC 166_ CLRPV 171_ CGRVS 176_ CHTTC 181_ YRPTC 186_ VISTC 191_ PRPLC 196_CASSC
1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins