F-box-like/WD repeat-containing protein TBL1Y (Transducin beta-like protein 1Y) (Transducin-beta-like protein 1, Y-linked)
1_MSITS 6_ DEVNF 11_ LVYRY 16_ LQESG 21_ FSHSA 26_ FTFGI 31_ ESHIS 36_ QSNIN 41_ GTLVP 46_ PSALI 51_ SILQK 56_ GLQYV 61_ EAEIS 66_ INKDG 71_ TVFDS 76_ RPIES 81_ LSLIV 86_ AVIPD 91_ VVQMR 96_ QQAFG 101_ EKLTQ 106_ QQASA 111_ AATEA 116_ SAMAK 121_ AATMT 126_ PAAIS 131_ QQNPP 136_ KNREA 141_ TVNGE 146_ ENGAH 151_ EINNH 156_ SKPME 161_ IDGDV 166_ EIPPN 171_ KATVL 176_ RGHES 181_ EVFIC 186_ AWNPV 191_ SDLLA 196_ SGSGD 201_ STARI 206_ WNLNE 211_ NSNGG 216_ STQLV 221_ LRHCI 226_ REGGH 231_ DVPSN 236_ KDVTS 241_ LDWNS 246_ DGTLL 251_ AMGSY 256_ DGFAR 261_ IWTEN 266_ GNLAS 271_ TLGQH 276_ KGPIF 281_ ALKWN 286_ KKGNY 291_ VLSAG 296_ VDKTT 301_ IIWDA 306_ HTGEA 311_ KQQFP 316_ FHSAP 321_ ALDVD 326_ WQNNM 331_ TFASC 336_ STDMC 341_ IHVCR 346_ LGCDH 351_ PVKTF 356_ QGHTN 361_ EVNAI 366_ KWDPS 371_ GMLLA 376_ SCSDD 381_ MTLKI 386_ WSMKQ 391_ DACVH 396_ DLQAH 401_ SKEIY 406_ TIKWS 411_ PTGPA 416_ TSNPN 421_ SSIML 426_ ASASF 431_ DSTVR 436_ LWDVE 441_ QGVCT 446_ HTLMK 451_ HQEPV 456_ YSVAF 461_ SPDGK 466_ YLASG 471_ SFDKY 476_ VHIWN 481_ TQSGS 486_ LVHSY 491_ QGTGG 496_ IFEVC 501_ WNARG 506_ DKVGA 511_ SASDG 516_SVCVL
1: F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange (By similarity)