Gene name: VKORC1

Uniprot entry:

Q9BQB6

Protein names:

Vitamin K epoxide reductase complex subunit 1 (EC 1.17.4.4) (Vitamin K1 2,3-epoxide reductase subunit 1)

Protein sequence:

1_MGSTW 6_ GSPGW 11_ VRLAL 16_ CLTGL 21_ VLSLY 26_ ALHVK 31_ AARAR 36_ DRDYR 41_ ALCDV 46_ GTAIS 51_ CSRVF 56_ SSRWG 61_ RGFGL 66_ VEHVL 71_ GQDSI 76_ LNQSN 81_ SIFGC 86_ IFYTL 91_ QLLLG 96_ CLRTR 101_ WASVL 106_ MLLSS 111_ LVSLA 116_ GSVYL 121_ AWILF 126_ FVLYD 131_ FCIVC 136_ ITTYA 141_ INVSL 146_ MWLSF 151_ RKVQE 156_PQGKA

Protein annotations

Protein functions:

1: Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development