Thioredoxin domain-containing protein 17 (14 kDa thioredoxin-related protein) (TRP14) (Protein 42-9-9) (Thioredoxin-like protein 5)
1_MARYE 6_ EVSVS 11_ GFEEF 16_ HRAVE 21_ QHNGK 26_ TIFAY 31_ FTGSK 36_ DAGGK 41_ SWCPD 46_ CVQAE 51_ PVVRE 56_ GLKHI 61_ SEGCV 66_ FIYCQ 71_ VGEKP 76_ YWKDP 81_ NNDFR 86_ KNLKV 91_ TAVPT 96_ LLKYG 101_ TPQKL 106_ VESEC 111_ LQANL 116_VEMLF
1: Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide