Protein fuzzy homolog
1_MGEEG 6_ TGGTV 11_ HLLCL 16_ AASSG 21_ VPLFC 26_ RSSRG 31_ GAPAR 36_ QQLPF 41_ SVIGS 46_ LNGVH 51_ MFGQN 56_ LEVQL 61_ SSART 66_ ENTTV 71_ VWKSF 76_ HDSIT 81_ LIVLS 86_ SEVGI 91_ SELRL 96_ ERLLQ 101_ MVFGA 106_ MVLLV 111_ GLEEL 116_ TNIRN 121_ VERLK 126_ KDLRA 131_ SYCLI 136_ DSFLG 141_ DSELI 146_ GDLTQ 151_ CVDCV 156_ IPPEG 161_ SLLQE 166_ ALSGF 171_ AEAAG 176_ TTFVS 181_ LVVSG 186_ RVVAA 191_ TEGWW 196_ RLGTP 201_ EAVLL 206_ PWLVG 211_ SLPPQ 216_ TARDY 221_ PVYLP 226_ HGSPT 231_ VPHRL 236_ LTLTL 241_ LPSLE 246_ LCLLC 251_ GPSPP 256_ LSQLY 261_ PQLLE 266_ RWWQP 271_ LLDPL 276_ RACLP 281_ LGPRA 286_ LPSGF 291_ PLHTD 296_ ILGLL 301_ LLHLE 306_ LKRCL 311_ FTVEP 316_ LGDKE 321_ PSPEQ 326_ RRRLL 331_ RNFYT 336_ LVTST 341_ HFPPE 346_ PGPPE 351_ KTEDE 356_ VYQAQ 361_ LPRAC 366_ YLVLG 371_ TEEPG 376_ TGVRL 381_ VALQL 386_ GLRRL 391_ LLLLS 396_ PQSPT 401_ HGLRS 406_ LATHT 411_LHALT
1: Probable planar cell polarity effector involved in cilium biogenesis. May regulate protein and membrane transport to the cilium. Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies. May regulate the morphogenesis of hair follicles which depends on functional primary cilia. Binds phosphatidylinositol 3-phosphate with highest affinity, followed by phosphatidylinositol 4-phosphate and phosphatidylinositol 5-phosphate (By similarity)