Gene name: FAAP24

Uniprot entry:

Q9BTP7

Protein names:

Fanconi anemia core complex-associated protein 24 (Fanconi anemia-associated protein of 24 kDa)

Protein sequence:

1_MEKNP 6_ PDDTG 11_ PVHVP 16_ LGHIV 21_ ANEKW 26_ RGSQL 31_ AQEMQ 36_ GKIKL 41_ IFEDG 46_ LTPDF 51_ YLSNR 56_ CCILY 61_ VTEAD 66_ LVAGN 71_ GYRKR 76_ LVRVR 81_ NSNNL 86_ KGIVV 91_ VEKTR 96_ MSEQY 101_ FPALQ 106_ KFTVL 111_ DLGMV 116_ LLPVA 121_ SQMEA 126_ SCLVI 131_ QLVQE 136_ QTKEP 141_ SKNPL 146_ LGKKR 151_ ALLLS 156_ EPSLL 161_ RTVQQ 166_ IPGVG 171_ KVKAP 176_ LLLQK 181_ FPSIQ 186_ QLSNA 191_ SIGEL 196_ EQVVG 201_ QAVAQ 206_QIHAF

Protein annotations

Protein functions:

1: Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA