Chordin-like protein 1 (Neuralin-1) (Neurogenesin-1) (Ventroptin)
1_MRKKW 6_ KMGGM 11_ KYIFS 16_ LLFFL 21_ LLEGG 26_ KTEQV 31_ KHSET 36_ YCMFQ 41_ DKKYR 46_ VGERW 51_ HPYLE 56_ PYGLV 61_ YCVNC 66_ ICSEN 71_ GNVLC 76_ SRVRC 81_ PNVHC 86_ LSPVH 91_ IPHLC 96_ CPRCP 101_ DSLPP 106_ VNNKV 111_ TSKSC 116_ EYNGT 121_ TYQHG 126_ ELFVA 131_ EGLFQ 136_ NRQPN 141_ QCTQC 146_ SCSEG 151_ NVYCG 156_ LKTCP 161_ KLTCA 166_ FPVSV 171_ PDSCC 176_ RVCRG 181_ DGELS 186_ WEHSD 191_ GDIFR 196_ QPANR 201_ EARHS 206_ YHRSH 211_ YDPPP 216_ SRQAG 221_ GLSRF 226_ PGARS 231_ HRGAL 236_ MDSQQ 241_ ASGTI 246_ VQIVI 251_ NNKHK 256_ HGQVC 261_ VSNGK 266_ TYSHG 271_ ESWHP 276_ NLRAF 281_ GIVEC 286_ VLCTC 291_ NVTKQ 296_ ECKKI 301_ HCPNR 306_ YPCKY 311_ PQKID 316_ GKCCK 321_ VCPGK 326_ KAKEL 331_ PGQSF 336_ DNKGY 341_ FCGEE 346_ TMPVY 351_ ESVFM 356_ EDGET 361_ TRKIA 366_ LETER 371_ PPQVE 376_ VHVWT 381_ IRKGI 386_ LQHFH 391_ IEKIS 396_ KRMFE 401_ ELPHF 406_ KLVTR 411_ TTLSQ 416_ WKIFT 421_ EGEAQ 426_ ISQMC 431_ SSRVC 436_ RTELE 441_ DLVKV 446_ LYLER 451_SEKGH
1: Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation (By similarity). May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development