Centromere protein O (CENP-O) (Interphase centromere complex protein 36)
1_MEQAN 6_ PLRPD 11_ GESKG 16_ GVLAH 21_ LERLE 26_ TQVSR 31_ SRKQS 36_ EELQS 41_ VQAQE 46_ GALGT 51_ KIHKL 56_ RRLRD 61_ ELRAV 66_ VRHRR 71_ ASVKA 76_ CIANV 81_ EPNQT 86_ VEINE 91_ QEALE 96_ EKLEN 101_ VKAIL 106_ QAYHF 111_ TGLSG 116_ KLTSR 121_ GVCVC 126_ ISTAF 131_ EGNLL 136_ DSYFV 141_ DLVIQ 146_ KPLRI 151_ HHHSV 156_ PVFIP 161_ LEEIA 166_ AKYLQ 171_ TNIQH 176_ FLFSL 181_ CEYLN 186_ AYSGR 191_ KYQAD 196_ RLQSD 201_ FAALL 206_ TGPLQ 211_ RNPLC 216_ NLLSF 221_ TYKLD 226_ PGGQS 231_ FPFCA 236_ RLLYK 241_ DLTAT 246_ LPTDV 251_ TVTCQ 256_ GVEVL 261_ STSWE 266_ EQRAS 271_ HETLF 276_ CTKPL 281_ HQVFA 286_ SFTRK 291_GEKLD
1: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Modulates the kinetochore-bound levels of NDC80 complex