Spondin-2 (Differentially expressed in cancerous and non-cancerous lung cells 1) (DIL-1) (Mindin)
1_MENPS 6_ PAAAL 11_ GKALC 16_ ALLLA 21_ TLGAA 26_ GQPLG 31_ GESIC 36_ SARAL 41_ AKYSI 46_ TFTGK 51_ WSQTA 56_ FPKQY 61_ PLFRP 66_ PAQWS 71_ SLLGA 76_ AHSSD 81_ YSMWR 86_ KNQYV 91_ SNGLR 96_ DFAER 101_ GEAWA 106_ LMKEI 111_ EAAGE 116_ ALQSV 121_ HAVFS 126_ APAVP 131_ SGTGQ 136_ TSAEL 141_ EVQRR 146_ HSLVS 151_ FVVRI 156_ VPSPD 161_ WFVGV 166_ DSLDL 171_ CDGDR 176_ WREQA 181_ ALDLY 186_ PYDAG 191_ TDSGF 196_ TFSSP 201_ NFATI 206_ PQDTV 211_ TEITS 216_ SSPSH 221_ PANSF 226_ YYPRL 231_ KALPP 236_ IARVT 241_ LVRLR 246_ QSPRA 251_ FIPPA 256_ PVLPS 261_ RDNEI 266_ VDSAS 271_ VPETP 276_ LDCEV 281_ SLWSS 286_ WGLCG 291_ GHCGR 296_ LGTKS 301_ RTRYV 306_ RVQPA 311_ NNGSP 316_ CPELE 321_ EEAEC 326_VPDNC
1: Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens (By similarity). Binds bacterial lipopolysaccharide (LPS)