Centrosome-associated protein CEP250 (250 kDa centrosomal protein) (Cep250) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Centrosomal protein 2)
1_METRS 6_ PGLNN 11_ MKPQS 16_ LQLVL 21_ EEQVL 26_ ALQQQ 31_ MAENQ 36_ AASWR 41_ KLKNS 46_ QEAQQ 51_ RQATL 56_ VRKLQ 61_ AKVLQ 66_ YRSWC 71_ QELEK 76_ RLEAT 81_ GGPIP 86_ QRWEN 91_ VEEPN 96_ LDELL 101_ VRLEE 106_ EQQRC 111_ ESLAE 116_ VNTQL 121_ RLHME 126_ KADVV 131_ NKALR 136_ EDVEK 141_ LTVDW 146_ SRARD 151_ ELMRK 156_ ESQWQ 161_ MEQEF 166_ FKGYL 171_ KGEHG 176_ RLLSL 181_ WREVV 186_ TFRRH 191_ FLEMK 196_ SATDR 201_ DLMEL 206_ KAEHV 211_ RLSGS 216_ LLTCC 221_ LRLTV 226_ GAQSR 231_ EPNGS 236_ GRMDG 241_ REPAQ 246_ LLLLL 251_ AKTQE 256_ LEKEA 261_ HERSQ 266_ ELIQL 271_ KSQGD 276_ LEKAE 281_ LQDRV 286_ TELSA 291_ LLTQS 296_ QKQNE 301_ DYEKM 306_ IKALR 311_ ETVEI 316_ LETNH 321_ TELME 326_ HEASL 331_ SRNAQ 336_ EEKLS 341_ LQQVI 346_ KDITQ 351_ VMVEE 356_ GDNIA 361_ QGSGH 366_ ENSLE 371_ LDSSI 376_ FSQFD 381_ YQDAD 386_ KALTL 391_ VRSVL 396_ TRRRQ 401_ AVQDL 406_ RQQLA 411_ GCQEA 416_ VNLLQ 421_ QQHDQ 426_ WEEEG 431_ KALRQ 436_ RLQKL 441_ TGERD 446_ TLAGQ 451_ TVDLQ 456_ GEVDS 461_ LSKER 466_ ELLQK 471_ AREEL 476_ RQQLE 481_ VLEQE 486_ AWRLR 491_ RVNVE 496_ LQLQG 501_ DSAQG 506_ QKEEQ 511_ QEELH 516_ LAVRE 521_ RERLQ 526_ EMLMG 531_ LEAKQ 536_ SESLS 541_ ELITL 546_ REALE 551_ SSHLE 556_ GELLR 561_ QEQTE 566_ VTAAL 571_ ARAEQ 576_ SIAEL 581_ SSSEN 586_ TLKTE 591_ VADLR 596_ AAAVK 601_ LSALN 606_ EALAL 611_ DKVGL 616_ NQQLL 621_ QLEEE 626_ NQSVC 631_ SRMEA 636_ AEQAR 641_ NALQV 646_ DLAEA 651_ EKRRE 656_ ALWEK 661_ NTHLE 666_ AQLQK 671_ AEEAG 676_ AELQA 681_ DLRDI 686_ QEEKE 691_ EIQKK 696_ LSESR 701_ HQQEA 706_ ATTQL 711_ EQLHQ 716_ EAKRQ 721_ EEVLA 726_ RAVQE 731_ KEALV 736_ REKAA 741_ LEVRL 746_ QAVER 751_ DRQDL 756_ AEQLQ 761_ GLSSA 766_ KELLE 771_ SSLFE 776_ AQQQN 781_ SVIEV 786_ TKGQL 791_ EVQIQ 796_ TVTQA 801_ KEVIQ 806_ GEVRC 811_ LKLEL 816_ DTERS 821_ QAEQE 826_ RDAAA 831_ RQLAQ 836_ AEQEG 841_ KTALE 846_ QQKAA 851_ HEKEV 856_ NQLRE 861_ KWEKE 866_ RSWHQ 871_ QELAK 876_ ALESL 881_ EREKM 886_ ELEMR 891_ LKEQQ 896_ TEMEA 901_ IQAQR 906_ EEERT 911_ QAESA 916_ LCQMQ 921_ LETEK 926_ ERVSL 931_ LETLL 936_ QTQKE 941_ LADAS 946_ QQLER 951_ LRQDM 956_ KVQKL 961_ KEQET 966_ TGILQ 971_ TQLQE 976_ AQREL 981_ KEAAR 986_ QHRDD 991_ LAALQ 996_ EESSS 1001_ LLQDK 1006_ MDLQK 1011_ QVEDL 1016_ KSQLV 1021_ AQDDS 1026_ QRLVE 1031_ QEVQE 1036_ KLRET 1041_ QEYNR 1046_ IQKEL 1051_ EREKA 1056_ SLTLS 1061_ LMEKE 1066_ QRLLV 1071_ LQEAD 1076_ SIRQQ 1081_ ELSAL 1086_ RQDMQ 1091_ EAQGE 1096_ QKELS 1101_ AQMEL 1106_ LRQEV 1111_ KEKEA 1116_ DFLAQ 1121_ EAQLL 1126_ EELEA 1131_ SHITE 1136_ QQLRA 1141_ SLWAQ 1146_ EAKAA 1151_ QLQLR 1156_ LRSTE 1161_ SQLEA 1166_ LAAEQ 1171_ QPGNQ 1176_ AQAQA 1181_ QLASL 1186_ YSALQ 1191_ QALGS 1196_ VCESR 1201_ PELSG 1206_ GGDSA 1211_ PSVWG 1216_ LEPDQ 1221_ NGARS 1226_ LFKRG 1231_ PLLTA 1236_ LSAEA 1241_ VASAL 1246_ HKLHQ 1251_ DLWKT 1256_ QQTRD 1261_ VLRDQ 1266_ VQKLE 1271_ ERLTD 1276_ TEAEK 1281_ SQVHT 1286_ ELQDL 1291_ QRQLS 1296_ QNQEE 1301_ KSKWE 1306_ GKQNS 1311_ LESEL 1316_ MELHE 1321_ TMASL 1326_ QSRLR 1331_ RAELQ 1336_ RMEAQ 1341_ GEREL 1346_ LQAAK 1351_ ENLTA 1356_ QVEHL 1361_ QAAVV 1366_ EARAQ 1371_ ASAAG 1376_ ILEED 1381_ LRTAR 1386_ SALKL 1391_ KNEEV 1396_ ESERE 1401_ RAQAL 1406_ QEQGE 1411_ LKVAQ 1416_ GKALQ 1421_ ENLAL 1426_ LTQTL 1431_ AEREE 1436_ EVETL 1441_ RGQIQ 1446_ ELEKQ 1451_ REMQK 1456_ AALEL 1461_ LSLDL 1466_ KKRNQ 1471_ EVDLQ 1476_ QEQIQ 1481_ ELEKC 1486_ RSVLE 1491_ HLPMA 1496_ VQERE 1501_ QKLTV 1506_ QREQI 1511_ RELEK 1516_ DRETQ 1521_ RNVLE 1526_ HQLLE 1531_ LEKKD 1536_ QMIES 1541_ QRGQV 1546_ QDLKK 1551_ QLVTL 1556_ ECLAL 1561_ ELEEN 1566_ HHKME 1571_ CQQKL 1576_ IKELE 1581_ GQRET 1586_ QRVAL 1591_ THLTL 1596_ DLEER 1601_ SQELQ 1606_ AQSSQ 1611_ IHDLE 1616_ SHSTV 1621_ LAREL 1626_ QERDQ 1631_ EVKSQ 1636_ REQIE 1641_ ELQRQ 1646_ KEHLT 1651_ QDLER 1656_ RDQEL 1661_ MLQKE 1666_ RIQVL 1671_ EDQRT 1676_ RQTKI 1681_ LEEDL 1686_ EQIKL 1691_ SLRER 1696_ GRELT 1701_ TQRQL 1706_ MQERA 1711_ EEGKG 1716_ PSKAQ 1721_ RGSLE 1726_ HMKLI 1731_ LRDKE 1736_ KEVEC 1741_ QQEHI 1746_ HELQE 1751_ LKDQL 1756_ EQQLQ 1761_ GLHRK 1766_ VGETS 1771_ LLLSQ 1776_ REQEI 1781_ VVLQQ 1786_ QLQEA 1791_ REQGE 1796_ LKEQS 1801_ LQSQL 1806_ DEAQR 1811_ ALAQR 1816_ DQELE 1821_ ALQQE 1826_ QQQAQ 1831_ GQEER 1836_ VKEKA 1841_ DALQG 1846_ ALEQA 1851_ HMTLK 1856_ ERHGE 1861_ LQDHK 1866_ EQARR 1871_ LEEEL 1876_ AVEGR 1881_ RVQAL 1886_ EEVLG 1891_ DLRAE 1896_ SREQE 1901_ KALLA 1906_ LQQQC 1911_ AEQAQ 1916_ EHEVE 1921_ TRALQ 1926_ DSWLQ 1931_ AQAVL 1936_ KERDQ 1941_ ELEAL 1946_ RAESQ 1951_ SSRHQ 1956_ EEAAR 1961_ ARAEA 1966_ LQEAL 1971_ GKAHA 1976_ ALQGK 1981_ EQHLL 1986_ EQAEL 1991_ SRSLE 1996_ ASTAT 2001_ LQASL 2006_ DACQA 2011_ HSRQL 2016_ EEALR 2021_ IQEGE 2026_ IQDQD 2031_ LRYQE 2036_ DVQQL 2041_ QQALA 2046_ QRDEE 2051_ LRHQQ 2056_ EREQL 2061_ LEKSL 2066_ AQRVQ 2071_ ENMIQ 2076_ EKQNL 2081_ GQERE 2086_ EEEIR 2091_ GLHQS 2096_ VRELQ 2101_ LTLAQ 2106_ KEQEI 2111_ LELRE 2116_ TQQRN 2121_ NLEAL 2126_ PHSHK 2131_ TSPME 2136_ EQSLK 2141_ LDSLE 2146_ PRLQR 2151_ ELERL 2156_ QAALR 2161_ QTEAR 2166_ EIEWR 2171_ EKAQD 2176_ LALSL 2181_ AQTKA 2186_ SVSSL 2191_ QEVAM 2196_ FLQAS 2201_ VLERD 2206_ SEQQR 2211_ LQDEL 2216_ ELTRR 2221_ ALEKE 2226_ RLHSP 2231_ GATST 2236_ AELGS 2241_ RGEQG 2246_ VQLGE 2251_ VSGVE 2256_ AEPSP 2261_ DGMEK 2266_ QSWRQ 2271_ RLEHL 2276_ QQAVA 2281_ RLEID 2286_ RSRLQ 2291_ RHNVQ 2296_ LRSTL 2301_ EQVER 2306_ ERRKL 2311_ KREAM 2316_ RAAQA 2321_ GSLEI 2326_ SKATA 2331_ SSPTQ 2336_ QDGRG 2341_ QKNSD 2346_ AKCVA 2351_ ELQKE 2356_ VVLLQ 2361_ AQLTL 2366_ ERKQK 2371_ QDYIT 2376_ RSAQT 2381_ SRELA 2386_ GLHHS 2391_ LSHSL 2396_ LAVAQ 2401_ APEAT 2406_ VLEAE 2411_ TRRLD 2416_ ESLTQ 2421_ SLTSP 2426_ GPVLL 2431_ HPSPS 2436_TTQAA
1: Plays an important role in centrosome cohesion during interphase (PubMed:30404835, PubMed:36282799). Recruits CCDC102B to the proximal ends of centrioles (PubMed:30404835). Maintains centrosome cohesion by forming intercentriolar linkages (PubMed:36282799). Accumulates at the proximal end of each centriole, forming supramolecular assemblies with viscous material properties that promote organelle cohesion (PubMed:36282799). May be involved in ciliogenesis (PubMed:28005958)