Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin)
1_MATPV 6_ VTKTA 11_ WKLQE 16_ IVAHA 21_ SNVSS 26_ LVLGK 31_ ASGRL 36_ LATGG 41_ DDCRV 46_ NLWSI 51_ NKPNC 56_ IMSLT 61_ GHTSP 66_ VESVR 71_ LNTPE 76_ ELIVA 81_ GSQSG 86_ SIRVW 91_ DLEAA 96_ KILRT 101_ LMGHK 106_ ANICS 111_ LDFHP 116_ YGEFV 121_ ASGSQ 126_ DTNIK 131_ LWDIR 136_ RKGCV 141_ FRYRG 146_ HSQAV 151_ RCLRF 156_ SPDGK 161_ WLASA 166_ ADDHT 171_ VKLWD 176_ LTAGK 181_ MMSEF 186_ PGHTG 191_ PVNVV 196_ EFHPN 201_ EYLLA 206_ SGSSD 211_ RTIRF 216_ WDLEK 221_ FQVVS 226_ CIEGE 231_ PGPVR 236_ SVLFN 241_ PDGCC 246_ LYSGC 251_ QDSLR 256_ VYGWE 261_ PERCF 266_ DVVLV 271_ NWGKV 276_ ADLAI 281_ CNDQL 286_ IGVAF 291_ SQSNV 296_ SSYVV 301_ DLTRV 306_ TRTGT 311_ VARDP 316_ VQDHR 321_ PLAQP 326_ LPNPS 331_ APLRR 336_ IYERP 341_ STTCS 346_ KPQRV 351_ KQNSE 356_ SERRS 361_ PSSED 366_ DRDER 371_ ESRAE 376_ IQNAE 381_ DYNEI 386_ FQPKN 391_ SISRT 396_ PPRRS 401_ EPFPA 406_ PPEDD 411_ AATAK 416_ EAAKP 421_ SPAMD 426_ VQFPV 431_ PNLEV 436_ LPRPP 441_ VVAST 446_ PAPKA 451_ EPAII 456_ PATRN 461_ EPIGL 466_ KASDF 471_ LPAVK 476_ IPQQA 481_ ELVDE 486_ DAMSQ 491_ IRKGH 496_ DTMCV 501_ VLTSR 506_ HKNLD 511_ TVRAV 516_ WTMGD 521_ IKTSV 526_ DSAVA 531_ INDLS 536_ VVVDL 541_ LNIVN 546_ QKASL 551_ WKLDL 556_ CTTVL 561_ PQIEK 566_ LLQSK 571_ YESYV 576_ QTGCT 581_ SLKLI 586_ LQRFL 591_ PLITD 596_ MLAAP 601_ PSVGV 606_ DISRE 611_ ERLHK 616_ CRLCY 621_ KQLKS 626_ ISGLV 631_ KSKSG 636_ LSGRH 641_ GSTFR 646_ELHLL
1: Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth