Gamma-glutamylaminecyclotransferase (GGACT) (EC 4.3.2.8) (AIG2-like domain-containing protein 1) (Gamma-glutamylamine cyclotransferase)
1_MALVF 6_ VYGTL 11_ KRGQP 16_ NHRVL 21_ RDGAH 26_ GSAAF 31_ RARGR 36_ TLEPY 41_ PLVIA 46_ GEHNI 51_ PWLLH 56_ LPGSG 61_ RLVEG 66_ EVYAV 71_ DERML 76_ RFLDD 81_ FESCP 86_ ALYQR 91_ TVLRV 96_ QLLED 101_ RAPGA 106_ EEPPA 111_ PTAVQ 116_ CFVYS 121_ RATFP 126_ PEWAQ 131_ LPHHD 136_ SYDSE 141_ GPHGL 146_RYNPR
1: Contributes to degradation of proteins cross-linked by transglutaminases by degrading the cross-link between a lysine and a glutamic acid residue. Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma-glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine