Max dimerization protein 3 (Max dimerizer 3) (Class C basic helix-loop-helix protein 13) (bHLHc13) (Max-associated protein 3) (Max-interacting transcriptional repressor MAD3) (Myx)
1_MEPLA 6_ SNIQV 11_ LLQAA 16_ EFLER 21_ REREA 26_ EHGYA 31_ SLCPH 36_ RSPGP 41_ IHRRK 46_ KRPPQ 51_ APGAQ 56_ DSGRS 61_ VHNEL 66_ EKRRR 71_ AQLKR 76_ CLERL 81_ KQQMP 86_ LGADC 91_ ARYTT 96_ LSLLR 101_ RARMH 106_ IQKLE 111_ DQEQR 116_ ARQLK 121_ ERLRS 126_ KQQSL 131_ QRQLE 136_ QLRGL 141_ AGAAE 146_ RERLR 151_ ADSLD 156_ SSGLS 161_ SERSD 166_ SDQEE 171_ LEVDV 176_ ESLVF 181_ GGEAE 186_ LLRGF 191_ VAGQE 196_ HSYSH 201_GGGAW
1: Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity)