Plasmalemma vesicle-associated protein (Fenestrated endothelial-linked structure protein) (Plasmalemma vesicle protein 1) (PV-1)
1_MGLAM 6_ EHGGS 11_ YARAG 16_ GSSRG 21_ CWYYL 26_ RYFFL 31_ FVSLI 36_ QFLII 41_ LGLVL 46_ FMVYG 51_ NVHVS 56_ TESNL 61_ QATER 66_ RAEGL 71_ YSQLL 76_ GLTAS 81_ QSNLT 86_ KELNF 91_ TTRAK 96_ DAIMQ 101_ MWLNA 106_ RRDLD 111_ RINAS 116_ FRQCQ 121_ GDRVI 126_ YTNNQ 131_ RYMAA 136_ IILSE 141_ KQCRD 146_ QFKDM 151_ NKSCD 156_ ALLFM 161_ LNQKV 166_ KTLEV 171_ EIAKE 176_ KTICT 181_ KDKES 186_ VLLNK 191_ RVAEE 196_ QLVEC 201_ VKTRE 206_ LQHQE 211_ RQLAK 216_ EQLQK 221_ VQALC 226_ LPLDK 231_ DKFEM 236_ DLRNL 241_ WRDSI 246_ IPRSL 251_ DNLGY 256_ NLYHP 261_ LGSEL 266_ ASIRR 271_ ACDHM 276_ PSLMS 281_ SKVEE 286_ LARSL 291_ RADIE 296_ RVARE 301_ NSDLQ 306_ RQKLE 311_ AQQGL 316_ RASQE 321_ AKQKV 326_ EKEAQ 331_ AREAK 336_ LQAEC 341_ SRQTQ 346_ LALEE 351_ KAVLR 356_ KERDN 361_ LAKEL 366_ EEKKR 371_ EAEQL 376_ RMELA 381_ IRNSA 386_ LDTCI 391_ KTKSQ 396_ PMMPV 401_ SRPMG 406_ PVPNP 411_ QPIDP 416_ ASLEE 421_ FKRKI 426_ LESQR 431_ PPAGI 436_PVAPS
1: Endothelial cell-specific membrane protein involved in the formation of the diaphragms that bridge endothelial fenestrae. It is also required for the formation of stomata of caveolae and transendothelial channels. Functions in microvascular permeability, endothelial fenestrae contributing to the passage of water and solutes and regulating transcellular versus paracellular flow in different organs. Plays a specific role in embryonic development