Gene name: AMN

Uniprot entry:

Q9BXJ7

Protein names:

Protein amnionless [Cleaved into: Soluble protein amnionless]

Protein sequence:

1_MGVLG 6_ RVLLW 11_ LQLCA 16_ LTQAV 21_ SKLWV 26_ PNTDF 31_ DVAAN 36_ WSQNR 41_ TPCAG 46_ GAVEF 51_ PADKM 56_ VSVLV 61_ QEGHA 66_ VSDML 71_ LPLDG 76_ ELVLA 81_ SGAGF 86_ GVSDV 91_ GSHLD 96_ CGAGE 101_ PAVFR 106_ DSDRF 111_ SWHDP 116_ HLWRS 121_ GDEAP 126_ GLFFV 131_ DAERV 136_ PCRHD 141_ DVFFP 146_ PSASF 151_ RVGLG 156_ PGASP 161_ VRVRS 166_ ISALG 171_ RTFTR 176_ DEDLA 181_ VFLAS 186_ RAGRL 191_ RFHGP 196_ GALSV 201_ GPEDC 206_ ADPSG 211_ CVCGN 216_ AEAQP 221_ WICAA 226_ LLQPL 231_ GGRCP 236_ QAACH 241_ SALRP 246_ QGQCC 251_ DLCGA 256_ VVLLT 261_ HGPAF 266_ DLERY 271_ RARIL 276_ DTFLG 281_ LPQYH 286_ GLQVA 291_ VSKVP 296_ RSSRL 301_ READT 306_ EIQVV 311_ LVENG 316_ PETGG 321_ AGRLA 326_ RALLA 331_ DVAEN 336_ GEALG 341_ VLEAT 346_ MRESG 351_ AHVWG 356_ SSAAG 361_ LAGGV 366_ AAAVL 371_ LALLV 376_ LLVAP 381_ PLLRR 386_ AGRLR 391_ WRRHE 396_ AAAPA 401_ GAPLG 406_ FRNPV 411_ FDVTA 416_ SEELP 421_ LPRRL 426_ SLVPK 431_ AAADS 436_ TSHSY 441_ FVNPL 446_FAGAE

Protein annotations

Protein functions:

1: Membrane-bound component of the endocytic receptor formed by AMN and CUBN (PubMed:14576052, PubMed:29402915, PubMed:30523278). Required for normal CUBN glycosylation and trafficking to the cell surface (PubMed:14576052, PubMed:29402915). The complex formed by AMN and CUBN is required for efficient absorption of vitamin B12 (PubMed:12590260, PubMed:14576052, PubMed:26040326). Required for normal CUBN-mediated protein transport in the kidney (Probable)