Gene name: MAP1LC3C

Uniprot entry:

Q9BXW4

Protein names:

Microtubule-associated proteins 1A/1B light chain 3C (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (MAP1A/MAP1B light chain 3 C) (MAP1A/MAP1B LC3 C) (Microtubule-associated protein 1 light chain 3 gamma)

Protein sequence:

1_MPPPQ 6_ KIPSV 11_ RPFKQ 16_ RKSLA 21_ IRQEE 26_ VAGIR 31_ AKFPN 36_ KIPVV 41_ VERYP 46_ RETFL 51_ PPLDK 56_ TKFLV 61_ PQELT 66_ MTQFL 71_ SIIRS 76_ RMVLR 81_ ATEAF 86_ YLLVN 91_ NKSLV 96_ SMSAT 101_ MAEIY 106_ RDYKD 111_ EDGFV 116_ YMTYA 121_ SQETF 126_ GCLES 131_ AAPRD 136_ GSSLE 141_DRPCN

Protein annotations

Protein functions:

1: Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2 (PubMed:23022382). Recruits all ATG8 family members to infecting bacteria such as S.typhimurium (PubMed:23022382). May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated and aggregated proteins (PubMed:28404643)