Gene name: HES7

Uniprot entry:

Q9BYE0

Protein names:

Transcription factor HES-7 (hHes7) (Class B basic helix-loop-helix protein 37) (bHLHb37) (Hairy and enhancer of split 7) (bHLH factor Hes7)

Protein sequence:

1_MVTRD 6_ RAENR 11_ DGPKM 16_ LKPLV 21_ EKRRR 26_ DRINR 31_ SLEEL 36_ RLLLL 41_ ERTRD 46_ QNLRN 51_ PKLEK 56_ AEILE 61_ FAVGY 66_ LRERS 71_ RVEPP 76_ GVPRS 81_ PVQDA 86_ EALAS 91_ CYLSG 96_ FRECL 101_ LRLAA 106_ FAHDA 111_ SPAAR 116_ AQLFS 121_ ALHGY 126_ LRPKP 131_ PRPKP 136_ VDPRP 141_ PAPRP 146_ SLDPA 151_ APALG 156_ PALHQ 161_ RPPVH 166_ QGHPS 171_ PRCAW 176_ SPSLC 181_ SPRAG 186_ DSGAP 191_ APLTG 196_ LLPPP 201_ PPPHR 206_ QDGAP 211_ KAPLP 216_PPPAF

Protein annotations

Protein functions:

1: Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation (By similarity)