Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B)
1_MNRSH 6_ RHGAG 11_ SGCLG 16_ TMEVK 21_ SKFGA 26_ EFRRF 31_ SLERS 36_ KPGKF 41_ EEFYG 46_ LLQHV 51_ HKIPN 56_ VDVLV 61_ GYADI 66_ HGDLL 71_ PINND 76_ DNYHK 81_ AVSTA 86_ NPLLR 91_ IFIQK 96_ KEEAD 101_ YSAFG 106_ TDTLI 111_ KKKNV 116_ LTNVL 121_ RPDNH 126_ RKKPH 131_ IVISM 136_ PQDFR 141_ PVSSI 146_ IDVDI 151_ LPETH 156_ RRVRL 161_ YKYGT 166_ EKPLG 171_ FYIRD 176_ GSSVR 181_ VTPHG 186_ LEKVP 191_ GIFIS 196_ RLVPG 201_ GLAQS 206_ TGLLA 211_ VNDEV 216_ LEVNG 221_ IEVSG 226_ KSLDQ 231_ VTDMM 236_ IANSR 241_ NLIIT 246_ VRPAN 251_ QRNNV 256_ VRNSR 261_ TSGSS 266_ GQSTD 271_ NSLLG 276_ YPQQI 281_ EPSFE 286_ PEDED 291_ SEEDD 296_ IIIED 301_ NGVPQ 306_ QIPKA 311_ VPNTE 316_ SLESL 321_ TQIEL 326_ SFESG 331_ QNGFI 336_ PSNEV 341_ SLAAI 346_ ASSSN 351_ TEFET 356_ HAPDQ 361_ KLLEE 366_DGTII
1: Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins