Gene name: KRTAP4-1

Uniprot entry:

Q9BYQ7

Protein names:

Keratin-associated protein 4-1 (Keratin-associated protein 4-10) (Keratin-associated protein 4.1) (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10)

Protein sequence:

1_MVNSC 6_ CGSVC 11_ SDQGC 16_ DQGLC 21_ QETCC 26_ RPSCC 31_ QTTCC 36_ CPSCV 41_ VSSCC 46_ RPSCS 51_ QTTCC 56_ QTTCC 61_ RPSCC 66_ HPVCC 71_ QTTCR 76_ PSCGV 81_ SSCCR 86_ PLCCQ 91_ TTCHP 96_ SCGMS 101_ SCCRP 106_ LCCQT 111_ TCRPS 116_ CGVSS 121_ CCRPL 126_ CCQTT 131_ CCRAT 136_ CCRPS 141_CCGSS

Protein annotations

Protein functions:

1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins