Gene name: KRTAP4-8

Uniprot entry:

Q9BYQ9

Protein names:

Keratin-associated protein 4-8 (Keratin-associated protein 4.8) (Ultrahigh sulfur keratin-associated protein 4.8)

Protein sequence:

1_MVNSC 6_ CGSVC 11_ SDQGC 16_ GQDLC 21_ QETCC 26_ CPSCC 31_ QTTCC 36_ RTTCY 41_ RPSYS 46_ VSCCC 51_ RPQCC 56_ QSVCC 61_ QPTCC 66_ RPSCC 71_ VSSCC 76_ KPQCC 81_ QSVCC 86_ QPTCC 91_ HPSCC 96_ ISSCC 101_ RPSCC 106_ VSSCC 111_ KPQCC 116_ QSVCC 121_ QPNCC 126_ RPSCS 131_ ISSCC 136_ RPSCC 141_ ESSCC 146_ RPCCC 151_ LRPVC 156_ GRVSC 161_ HTTCY 166_ RPACV 171_ ISTCP 176_RPVCC

Protein annotations

Protein functions:

1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins