Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5)
1_MVSSC 6_ CGSVS 11_ SEQSC 16_ GLENC 21_ CRPSC 26_ CQTTC 31_ CRTTC 36_ CRPSC 41_ CKPQC 46_ CQSVC 51_ YQPTC 56_ CHPSC 61_ CISSC 66_ CRPYC 71_ CESSC 76_ CRPCC 81_ CQTTC 86_ CRTTC 91_ CRTTC 96_ CCPSC 101_ CVSSC 106_ CRPQC 111_ CQSVC 116_ CQPTC 121_ CRPSC 126_ CISSC 131_ CHPSC 136_ CESSC 141_ CRPCC 146_ CVRPV 151_ CGRVS 156_ CHTTC 161_ YRPTC 166_ VISTC 171_ PRPLC 176_CASSC
1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins