Gene name: KRTAP4-3

Uniprot entry:

Q9BYR4

Protein names:

Keratin-associated protein 4-3 (Keratin-associated protein 4.3) (Ultrahigh sulfur keratin-associated protein 4.3)

Protein sequence:

1_MVSSC 6_ CGSVC 11_ SDQSC 16_ GQGLG 21_ QESCC 26_ RPSCC 31_ QTTCC 36_ RTTCC 41_ RPSCC 46_ ISSCC 51_ RPSCC 56_ ISSCC 61_ KPSCC 66_ RTTCC 71_ RPSCC 76_ ISSCC 81_ RPSCC 86_ ISSCC 91_ KPSCC 96_ RTTCC 101_ RPSCC 106_ ISSCC 111_ RPSCC 116_ ISSCC 121_ KPSCC 126_ QTTCC 131_ RPSCC 136_ ISSCY 141_ RPQCC 146_ QPSCC 151_ RPACC 156_ ISSCC 161_ HPSCC 166_ VSSCR 171_ CPFSC 176_ PTTCC 181_ RTTCF 186_HPICC

Protein annotations

Protein functions:

1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins