Gene name: KRTAP2-2

Uniprot entry:

Q9BYT5

Protein names:

Keratin-associated protein 2-2 (High sulfur keratin-associated protein 2.2) (Keratin-associated protein 2.2)

Protein sequence:

1_MTGSC 6_ CGSTF 11_ SSLSY 16_ GGGCC 21_ QPCCC 26_ RDPCC 31_ CRPVT 36_ CQTTV 41_ CRPVT 46_ CVPRC 51_ TRPIC 56_ EPCRR 61_ PVCCD 66_ PCSLQ 71_ EGCCR 76_ PITCC 81_ PSSCT 86_ AVVCR 91_ PCCWA 96_ TTCCQ 101_ PVSVQ 106_ SPCGQ 111_ PTPCS 116_TTCRT

Protein annotations

Protein functions:

1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity)