CUGBP Elav-like family member 4 (CELF-4) (Bruno-like protein 4) (CUG-BP- and ETR-3-like factor 4) (RNA-binding protein BRUNOL-4)
1_MYIKM 6_ ATLAN 11_ GQADN 16_ ASLST 21_ NGLGS 26_ SPGSA 31_ GHMNG 36_ LSHSP 41_ GNPST 46_ IPMKD 51_ HDAIK 56_ LFIGQ 61_ IPRNL 66_ DEKDL 71_ KPLFE 76_ EFGKI 81_ YELTV 86_ LKDRF 91_ TGMHK 96_ GCAFL 101_ TYCER 106_ ESALK 111_ AQSAL 116_ HEQKT 121_ LPGMN 126_ RPIQV 131_ KPADS 136_ ESRGG 141_ SSCLR 146_ QPPSQ 151_ DRKLF 156_ VGMLN 161_ KQQSE 166_ DDVRR 171_ LFEAF 176_ GNIEE 181_ CTILR 186_ GPDGN 191_ SKGCA 196_ FVKYS 201_ SHAEA 206_ QAAIN 211_ ALHGS 216_ QTMPG 221_ ASSSL 226_ VVKFA 231_ DTDKE 236_ RTMRR 241_ MQQMA 246_ GQMGM 251_ FNPMA 256_ IPFGA 261_ YGAYA 266_ QALMQ 271_ QQAAL 276_ MASVA 281_ QGGYL 286_ NPMAA 291_ FAAAQ 296_ MQQMA 301_ ALNMN 306_ GLAAA 311_ PMTPT 316_ SGGST 321_ PPGIT 326_ APAVP 331_ SIPSP 336_ IGVNG 341_ FTGLP 346_ PQANG 351_ QPAAE 356_ AVFAN 361_ GIHPY 366_ PAQSP 371_ TAADP 376_ LQQAY 381_ AGVQQ 386_ YAGPA 391_ AYPAA 396_ YGQIS 401_ QAFPQ 406_ PPPMI 411_ PQQQR 416_ EGPEG 421_ CNLFI 426_ YHLPQ 431_ EFGDA 436_ ELMQM 441_ FLPFG 446_ FVSFD 451_ NPASA 456_ QTAIQ 461_ AMNGF 466_ QIGMK 471_ RLKVQ 476_ LKRPK 481_DANRP
1: RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Promotes exclusion of both the smooth muscle (SM) and non-muscle (NM) exons in actinin pre-mRNAs. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA