Apoptosis inhibitor 5 (API-5) (Antiapoptosis clone 11 protein) (AAC-11) (Cell migration-inducing gene 8 protein) (Fibroblast growth factor 2-interacting factor) (FIF) (Protein XAGL)
1_MPTVE 6_ ELYRN 11_ YGILA 16_ DATEQ 21_ VGQHK 26_ DAYQV 31_ ILDGV 36_ KGGTK 41_ EKRLA 46_ AQFIP 51_ KFFKH 56_ FPELA 61_ DSAIN 66_ AQLDL 71_ CEDED 76_ VSIRR 81_ QAIKE 86_ LPQFA 91_ TGENL 96_ PRVAD 101_ ILTQL 106_ LQTDD 111_ SAEFN 116_ LVNNA 121_ LLSIF 126_ KMDAK 131_ GTLGG 136_ LFSQI 141_ LQGED 146_ IVRER 151_ AIKFL 156_ STKLK 161_ TLPDE 166_ VLTKE 171_ VEELI 176_ LTESK 181_ KVLED 186_ VTGEE 191_ FVLFM 196_ KILSG 201_ LKSLQ 206_ TVSGR 211_ QQLVE 216_ LVAEQ 221_ ADLEQ 226_ TFNPS 231_ DPDCV 236_ DRLLQ 241_ CTRQA 246_ VPLFS 251_ KNVHS 256_ TRFVT 261_ YFCEQ 266_ VLPNL 271_ GTLTT 276_ PVEGL 281_ DIQLE 286_ VLKLL 291_ AEMSS 296_ FCGDM 301_ EKLET 306_ NLRKL 311_ FDKLL 316_ EYMPL 321_ PPEEA 326_ ENGEN 331_ AGNEE 336_ PKLQF 341_ SYVEC 346_ LLYSF 351_ HQLGR 356_ KLPDF 361_ LTAKL 366_ NAEKL 371_ KDFKI 376_ RLQYF 381_ ARGLQ 386_ VYIRQ 391_ LRLAL 396_ QGKTG 401_ EALKT 406_ EENKI 411_ KVVAL 416_ KITNN 421_ INVLI 426_ KDLFH 431_ IPPSY 436_ KSTVT 441_ LSWKP 446_ VQKVE 451_ IGQKR 456_ ASEDT 461_ TSGSP 466_ PKKSS 471_ AGPKR 476_ DARQI 481_ YNPPS 486_ GKYSS 491_ NLGNF 496_ NYEQR 501_ GAFRG 506_ SRGGR 511_ GWGTR 516_GNRSR
1: Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs