Phosphatase and actin regulator 1
1_MDYPK 6_ MDYFL 11_ DVESA 16_ HRLLD 21_ VESAQ 26_ RFFYS 31_ QGAQA 36_ RRATL 41_ LLPPT 46_ LMAAS 51_ SEDDI 56_ DRRPI 61_ RRVRS 66_ KSDTP 71_ YLAEA 76_ RISFN 81_ LGAAE 86_ EVERL 91_ AAMRS 96_ DSLVP 101_ GTHTP 106_ PIRRR 111_ SKFAN 116_ LGRIF 121_ KPWKW 126_ RKKKS 131_ EKFKH 136_ TSAAL 141_ ERKIS 146_ MRQSR 151_ EELIK 156_ RGVLK 161_ EIYDK 166_ DGELS 171_ ISNEE 176_ DSLEN 181_ GQSLS 186_ SSQLS 191_ LPALS 196_ EMEPV 201_ PMPRD 206_ PCSYE 211_ VLQPS 216_ DIMDG 221_ PDPGA 226_ PVKLP 231_ CLPVK 236_ LSPPL 241_ PPKKV 246_ MICMP 251_ VGGPD 256_ LSLVS 261_ YTAQK 266_ SGQQG 271_ VAQHH 276_ HTVLP 281_ SQIQH 286_ QLQYG 291_ SHGQH 296_ LPSTT 301_ GSLPM 306_ HPSGC 311_ RMIDE 316_ LNKTL 321_ AMTMQ 326_ RLESS 331_ EQRVP 336_ CSTSY 341_ HSSGL 346_ HSGDG 351_ VTKAG 356_ PMGLP 361_ EIRQV 366_ PTVVI 371_ ECDDN 376_ KENVP 381_ HESDY 386_ EDSSC 391_ LYTRE 396_ EEEEE 401_ EDEDD 406_ DSSLY 411_ TSSLA 416_ MKVCR 421_ KDSLA 426_ IKLSN 431_ RPSKR 436_ ELEEK 441_ NILPR 446_ QTDEE 451_ RLELR 456_ QQIGT 461_ KLTRR 466_ LSQRP 471_ TAEEL 476_ EQRNI 481_ LKPRN 486_ EQEEQ 491_ EEKRE 496_ IKRRL 501_ TRKLS 506_ QRPTV 511_ EELRE 516_ RKILI 521_ RFSDY 526_ VEVAD 531_ AQDYD 536_ RRADK 541_ PWTRL 546_ TAADK 551_ AAIRK 556_ ELNEF 561_ KSTEM 566_ EVHEL 571_SRHLT
1: Binds actin monomers (G actin) and plays a role in multiple processes including the regulation of actin cytoskeleton dynamics, actin stress fibers formation, cell motility and survival, formation of tubules by endothelial cells, and regulation of PPP1CA activity (PubMed:21798305, PubMed:21939755). Involved in the regulation of cortical neuron migration and dendrite arborization (By similarity)