FH2 domain-containing protein 1 (Inverted formin-1)
1_MHVMN 6_ CVSLV 11_ SDKEN 16_ GNIAT 21_ APGFM 26_ IGQTP 31_ PPAPP 36_ PPPPP 41_ PPPSP 46_ PCSCS 51_ REECP 56_ SSPPP 61_ PPPPP 66_ LPGEP 71_ PIPPP 76_ PPGLP 81_ PTTHM 86_ NGYSH 91_ LGKKK 96_ RMRSF 101_ FWKTI 106_ PEEQV 111_ RGKTN 116_ IWTLA 121_ ARQEH 126_ HYQID 131_ TKTIE 136_ ELFGQ 141_ QEDTT 146_ KSSLP 151_ RRGRT 156_ LNSSF 161_ REARE 166_ EITIL 171_ DAKRS 176_ MNIGI 181_ FLKQF 186_ KKSPR 191_ SIVED 196_ IHQGK 201_ SEHYG 206_ SETLR 211_ EFLKF 216_ LPESE 221_ EVKKL 226_ KAFSG 231_ DVSKL 236_ SLADS 241_ FLYGL 246_ IQVPN 251_ YSLRI 256_ EAMVL 261_ KKEFL 266_ PSCSS 271_ LYTDI 276_ TVLRT 281_ AIKEL 286_ MSCEE 291_ LHSIL 296_ HLVLQ 301_ AGNIM 306_ NAGGY 311_ AGNAV 316_ GFKLS 321_ SLLKL 326_ ADTKA 331_ NKPGM 336_ NLLHF 341_ VAQEA 346_ QKKDT 351_ ILLNF 356_ SEKLH 361_ HVQKT 366_ ARLSL 371_ ENTEA 376_ ELHLL 381_ FVRTK 386_ SLKEN 391_ IQRDG 396_ ELCQQ 401_ MEDFL 406_ QFAIE 411_ KLREL 416_ ECWKQ 421_ ELQDE 426_ AYTLI 431_ DFFCE 436_ DKKTM 441_ KLDEC 446_ FQIFR 451_ DFCTK 456_ FNKAV 461_ KDNHD 466_ REAQE 471_ LRQLQ 476_ RLKEQ 481_ EQKQR 486_ SWATG 491_ ELGAF 496_ GRSSS 501_ ENDVE 506_ LLTKK 511_ GAEGL 516_ LPFLH 521_ PRPIS 526_ PSSPS 531_ YRPPN 536_ TRRSR 541_ LSLGP 546_ SADRE 551_ LLTFL 556_ ESSTG 561_ SPEEP 566_ NKFHS 571_ LPRSS 576_ PRQAR 581_ PTIAC 586_ LEPAE 591_ VRHQD 596_ SSFAH 601_ KPQAS 606_ GGQEE 611_ APNPP 616_ SAQAH 621_ QLAAA 626_ QPENH 631_ ASAFP 636_ RARRQ 641_ GVSVL 646_ RKRYS 651_ EPVSL 656_ GSAQS 661_ PPLSP 666_ LALGI 671_ KEHEL 676_ VTGLA 681_ QFNLQ 686_ GSQGM 691_ EETSQ 696_ LTLSD 701_ FSPME 706_ LESVG 711_ HRGPQ 716_ SLSAS 721_ SSSLT 726_ PMGRD 731_ ALGSL 736_ SPALE 741_ DGKAA 746_ PDEPG 751_ SAALG 756_ SVGSS 761_ DPENK 766_ DPRPL 771_ FCISD 776_ TTDCS 781_ LTLDC 786_ SEGTD 791_ SRPRG 796_ GDPEE 801_ GGEGD 806_ GSMSS 811_ GVGEM 816_ GDSQV 821_ SSNPT 826_ SSPPG 831_ EAPAP 836_ VSVDS 841_ EPSCK 846_ GGLPR 851_ DKPTK 856_ RKDVV 861_ APKRG 866_ SLKEA 871_ SPGAS 876_ KPGSA 881_ RRSQG 886_ AVAKS 891_ VRTLT 896_ ASENE 901_ SMRKV 906_ MPITK 911_ SSRGA 916_ GWRRP 921_ ELSSR 926_ GPSQN 931_ PPSST 936_ DTVWS 941_ RQNSV 946_ RRAST 951_ GAEEQ 956_ RLPRG 961_ SSGSS 966_ STRPG 971_ RDVPL 976_ QPRGS 981_ FKKPS 986_ AKPLR 991_ NLPRQ 996_ KPEEN 1001_ KTCRA 1006_ HSEGP 1011_ ESPKE 1016_ EPKTP 1021_ SVPSV 1026_ PHELP 1031_ RVPSF 1036_ ARNTV 1041_ ASSSR 1046_ SMRTD 1051_ LPPVA 1056_ KAPGI 1061_ TRTVS 1066_ QRQLR 1071_ VKGDP 1076_ EDAAP 1081_ KDSST 1086_ LRRAS 1091_ SARAP 1096_ KKRPE 1101_ SAEGP 1106_ SANTE 1111_ APLKA 1116_ RGAGE 1121_ RASLR 1126_ RKDSS 1131_ RTTLG 1136_RILNP
1: Microtubule-associated formin which regulates both actin and microtubule dynamics. Induces microtubule acetylation and stabilization and actin stress fiber formation (PubMed:18815276). Regulates Golgi ribbon formation (PubMed:26564798). Required for normal cilia assembly. Early in cilia assembly, may assist in the maturation and positioning of the centrosome/basal body, and once cilia assembly has initiated, may also promote cilia elongation by inhibiting disassembly (PubMed:29742020)