Homeobox protein TGIF2 (5'-TG-3'-interacting factor 2) (TGF-beta-induced transcription factor 2) (TGFB-induced factor 2)
1_MSDSD 6_ LGEDE 11_ GLLSL 16_ AGKRK 21_ RRGNL 26_ PKESV 31_ KILRD 36_ WLYLH 41_ RYNAY 46_ PSEQE 51_ KLSLS 56_ GQTNL 61_ SVLQI 66_ CNWFI 71_ NARRR 76_ LLPDM 81_ LRKDG 86_ KDPNQ 91_ FTISR 96_ RGGKA 101_ SDVAL 106_ PRGSS 111_ PSVLA 116_ VSVPA 121_ PTNVL 126_ SLSVC 131_ SMPLH 136_ SGQGE 141_ KPAAP 146_ FPRGE 151_ LESPK 156_ PLVTP 161_ GSTLT 166_ LLTRA 171_ EAGSP 176_ TGGLF 181_ NTPPP 186_ TPPEQ 191_ DKEDF 196_ SSFQL 201_ LVEVA 206_ LQRAA 211_ EMELQ 216_ KQQDP 221_ SLPLL 226_ HTPIP 231_LVSEN
1: Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins