Gene name: PITHD1

Uniprot entry:

Q9GZP4

Protein names:

PITH domain-containing protein 1

Protein sequence:

1_MSHGH 6_ SHGGG 11_ GCRCA 16_ AEREE 21_ PPEQR 26_ GLAYG 31_ LYLRI 36_ DLERL 41_ QCLNE 46_ SREGS 51_ GRGVF 56_ KPWEE 61_ RTDRS 66_ KFVES 71_ DADEE 76_ LLFNI 81_ PFTGN 86_ VKLKG 91_ IIIMG 96_ EDDDS 101_ HPSEM 106_ RLYKN 111_ IPQMS 116_ FDDTE 121_ REPDQ 126_ TFSLN 131_ RDLTG 136_ ELEYA 141_ TKISR 146_ FSNVY 151_ HLSIH 156_ ISKNF 161_ GADTT 166_ KVFYI 171_ GLRGE 176_ WTELR 181_ RHEVT 186_ ICNYE 191_ ASANP 196_ ADHRV 201_ HQVTP 206_QTHFI

Protein annotations

Protein functions:

1: Promotes megakaryocyte differentiation by up-regulating RUNX1 expression (PubMed:25134913). Regulates RUNX1 expression by activating the proximal promoter of the RUNX1 gene and by enhancing the translation activity of an internal ribosome entry site (IRES) element in the RUNX1 gene (PubMed:25134913)